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The Most Common Rheumatic Disorders

The Most Common Rheumatic Disorders

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Osteoarthritis is the most common type of Rheumatic Disorder. This affects about 27 million adults in the United States alone. Osteoarthritis is a chronic condition characterized by the breakdown of the joint’s cartilage. 

The breakdown of cartilage causes the bones to rub against each other, causing stiffness, pain, and loss of movement in the joint. Patients who have been diagnosed with Osteoarthritis are generally cared for by an Orthopedic Specialist.

What are the Risk Factors of Rheumatic Disorder?

The rheumatic disorder can develop in people of any age, sex, or race. There are several different forms of rheumatic disorder and some people are more susceptible to some than others. Some contributing factors to the disease include age, gender, genetics, and environmental factors. Some people are at higher risk for developing a rheumatic disorder, including those people who carry the PTPN22 gene, women, Hispanics, and African Americans.

Common Types of Rheumatic Disorder

hand arthritis in x ray

What Causes Rheumatic Disorder?

In many cases, the cause depends on the type of rheumatic disorder. But researchers believe that some or all of the following may play a role:

  • Genes and family history
  • Lifestyle choices such as being overweight
  • Trauma
  • Infection
  • Nervous system problems
  • Metabolic problems
  • Too much wear and tear and stress on a joint or joints
  • Environmental triggers
  • Certain hormones

Rheumatic Disorder Diagnosis

Diagnosis of rheumatic disorder begins with a discussion of your medical history. Your doctor will talk with you about your symptoms, including:

  • How much pain you’re in
  • Factors that worsen the pain
  • Where you feel pain or other symptoms
  • When your symptoms began and whether they’re constant or change throughout the day
  • Drugs, body positions, and other things that may relieve your symptoms
Medications Used For Kidney Infection

Rheumatic Disorder Treatment

Various types of medication are prescribed to treat rheumatic disorder. Some drugs only treat symptoms like pain and inflammation, while others can alter the course of the disease.

Depending on the condition, medication may include:

  • Prednisolone – this medicine is a man-made form of a natural substance (corticosteroid hormone) made by the adrenal gland. Prednisolone lessens the immune system’s response to various diseases to reduce symptoms such as pain and swelling.

Medicine that is usually recommended for rheumatic disorder:

Besides medication, various other types of treatments may be prescribed for a rheumatic disorder such as:

  • Physical therapy
  • Hot and cold therapy
  • Occupational therapy
  • Relaxation therapy
  • Specific exercise regimes to increase muscle strength and joint flexibility
  • Splints, braces, and assistive devices to support weak joints
  • Surgery
What Condition Does Sodium Hyaluronate Treat and Its Price

What Condition Does Sodium Hyaluronate Treat and Its Price?

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Sodium Hyaluronate is an intra-articular injection. It is indicated for the management and treatment of pain in the knee due to osteoarthritis. It is meant to be used in patients who do not get effective pain relief from simple pain medication and therapy. This medicine has recently been approved in the US. It works directly into the knee by injection.

What condition does Sodium Hyaluronate treat?

Sodium hyaluronate is used for the treatment of knee pain due to arthritis. It is usually given to patients when all other arthritis medications have not been effective.

How does Sodium Hyaluronate work?

Sodium Hyaluronate is naturally found all over the body. It is somewhat like joint fluid, which is all over the body. Sodium hyaluronate is a thick elastic polymer particularly in areas of the body that need lubrication. It acts as a lubricant and shock absorber for the joints.

Knee osteoarthritis, also known as degenerative joint disease, is the result of wear and friction. This type of arthritis is very common in older adults. Common clinical symptoms may include:

  • Knee stiffness and swelling
  • Knee pain that’s gradual in onset and worsens with movement
  • Pain after prolonged resting or sitting

The exact way how this injection work is not well understood. It is believed that it helps support the cartilages and restore the synovial fluid in the knee. As a result, reducing also the pain and swelling associated with osteoarthritis.

What is the dosage of Sodium Hyaluronate?

Sodium Hyaluronate is injected directly into the knee joint. Your doctor will provide you with the injection, typically, 20 milligrams once a week. It is usually injected every week for 3 to 5 weeks for a total of five injections.

Use it very carefully. Your doctor may recommend you to rest your knee or apply ice for a short time after injecting to prevent pain and swelling.

What are the precautions in using Sodium Hyaluronate?

  • Make sure that this prescription is right for you. If in doubt, you can ask and consult your doctor before using Sodium Hyaluronate.
  • Let your pharmacist or doctor know if you have ever had an allergic reaction to a preservative in injection or if you have any allergies.
  • Tell your healthcare team if you are using a product that contains chlorhexidine or ammonium salts.
  • Tell as well if you have bleeding problems, blood clots, or circulation problems in your legs.
  • If you have prescriptions, non-prescription medication, vitamins, herbal products, or food supplements, inform also your doctor or healthcare team.
  • Before you start using Sodium Hyaluronate, carefully read the manufacturer’s information. It will give you more information about using the drops.
  • Do not wear soft contact lenses while you are using the drops unless it is advised otherwise. There is a preservative in bottles of eye drops that may affect soft contact lenses.
  • See your doctor right away if your symptoms do not improve within a few days.
  • Do not use the injection if you have an infection in your knee or the skin area around the knee.
  • Avoid doing strenuous activities that put lots of weight on your legs for the first 48 hours after receiving the injection. These activities include heavy lifting, jogging, playing tennis, or prolonged standing.
  • Patients below 21 years of age should not use this product.
  • It is not known whether this medication can harm an unborn baby. Inform your doctor if you are pregnant or planning to become pregnant before using this injection.

Price of Sodium Hyaluronate vs. Hyalgan

Sodium Hyaluronate is an effective medicine in reducing knee pain caused by arthritis.  The price of 1 syringe of 20mg 2ml is $59 only for sodium hyaluronate at rx2go.com. The brand name Hyalgan cost $146.86 per 1 syringe of 20mg 2ml.

Treating Osteoarthritis, Rheumatoid & Juvenile Rheumatoid Arthritis

Treating Osteoarthritis, Rheumatoid & Juvenile Rheumatoid Arthritis

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Meloxicam is an oral prescription drug. It is prescribed to people with pain, swelling and tenderness due to arthritis. Meloxicam blocks a certain enzyme in your body that causes inflammation. As a result, swelling and other symptoms will reduce.

It is available in tablet, capsule and liquid suspension.

What condition does Meloxicam treats?

Meloxicam can treat:

How does Meloxicam works?

Meloxicam is a non-steroidal anti-inflammatory drug (NSAID). It works by lowering the levels of prostaglandins in your body. Prostaglandins are chemicals that cause swelling.  NSAID helps reduce the symptoms of arthritis such as:

  • Fever
  • Pain
  • Tenderness
  • Swelling

What is the dose of Meloxicam?

Adult dosage

-Initial dose: 7.5 mg a day

-Maintenance dose: 10 mg a day

-Maximum dose: 10 mg a day

Children’s dosage

-For children with juvenile arthritis, the dose is 0.125 mg/kg daily up to 7.5 mg per day.

The lowest effective dose is recommended for each patient. Some may require a higher dose. Talk to your doctor if you need a higher dose.

How to take Meloxicam?

  • Take this medicine as directed by your doctor.
  • Take the medicine orally with or without food.
  • Swallow the tablet whole. Do not let it melt in your mouth.
  • To prevent stomach upset, do not lie down for at least 30 minutes after taking this medicine.
  • Take the lowest effective dose.
  • Do not take more than the recommended dose or longer than the required time.
  • For liquid suspension, shake the medicine well before each dose.

What are the precautions in taking Meloxicam?

  • Make sure this medicine is safe for you to take. Tell your doctor if you have:
    • Allergies
    • Heart disease
    • Seizure
    • Kidney and liver disease
    • Asthma
    • You’re taking other medicines
    • If you smoke
  • Do not take this medicine before or after a heart bypass surgery.
  • Do not take this if you’re pregnant.
  • This medicine is not recommended for children less than 2 years of age.
  • This medicine may increase your risk of developing blood clot at higher dose. Talk to your doctor about this.
  • Avoid drinking alcohol. This medicine may cause stomach bleeding.

Costs of Generic Meloxicam vs Brand Mobic

The generic brand Meloxicam is cheaper than the brand name Mobic. Meloxicam 15 mg costs $0.5 per unit price or $15.00 for 30 pills. While the branded Mobic 15 mg costs $11.86 per unit price or $355.69 for 30 pills.

Buy Celecoxib

Cobix (Celecoxib)

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Cobix (Celecoxib) is a prescription medication. It is intended for the treatment of arthritis, spondylitis and for the management of acute pain. It is a non-steroidal anti-inflammatory drug (NSAID). It helps relieve pain, fever, swelling and tenderness due to:

  • Osteoarthritis
  • Rheumatoid arthritis
  • Juvenile rheumatoid arthritis in children 2 years of age and older

It is also used to reduce painful menstrual cramps and short-term pain due to injuries and medical procedures. It works by blocking the enzyme that makes prostaglandins. These chemicals are an important contributor to inflammation

of arthritis. Lowering the level of the enzyme reduces the swelling, pain, tenderness and inflammation of arthritis.

Why Buy Celecoxib?

Celecoxib exerts an anti-inflammatory, analgesic and antipyretic actions with low ulcerogenic potential. Cobix is a lot cheaper than its brand names available in the market. However, both the generic and the branded counterpart contains the same active ingredients. They have the same mechanism of action and safety. Unlike other NSAID, this drug does not interfere with blood clotting. It also causes less ulceration and swelling of intestine and stomach.

How to Take Celecoxib?

Celecoxib is available in different doses. Take this drug exactly as instructed. Do not take more than what is prescribed. Take this medication with a glass of water. You should take it with food to prevent stomach upset.

For acute pain and menstrual cramps

Take 400mg of Celecoxib as an initial dose. Then take 200mg only as needed or every 12 hours on the subsequent days.

Ankylosing Spondylitis

Take 200 mg once a day or in divided doses every 12 hours. You may increase your dose to 400mg a day if there is no response to the initial dose. Discontinue therapy if there is no adequate response after taking the medication for 6 weeks.

Osteoarthritis

Take 200mg of Celecoxib once a day or every 12 hours.

Juvenile Rheumatoid arthritis

Children weighing 10-25 kg must take 50 mg of this medication every 12 hours. Those weighing 25kg must take 100mg orally every 12 hours.

Things to Remember

  • Celecoxib may interact with other drugs. However, there are no severe interactions with other drugs have been reported.
  • Prolonged use of this medication with other NSAID may increase the risk of intestinal and stomach ulcers.
  • People with high blood pressure, heart failure, kidney and liver problems must take this drug with caution.
  • This drug may cause side effects. Tell your doctor if you experience serious side effects such as:
    •  severe allergic reaction
    • signs of kidney and liver problems
    • difficulty swallowing.
Buy Celecoxib

Medication To Treat Osteoarthritis, Rheumatoid , Ankylosing, Juvenile Rheumatoid Arthritis

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Celecoxib is a prescription anti-inflammatory medication. It belongs to the group of drug known as selective COX-2 inhibitors, a kind of non-steroidal anti-inflammatory drug (NSAID). It is prescribed for the treatment of conditions like:

  • Osteoarthritis –caused by the breakdown of the lining of the joints
  • Rheumatoid arthritis- swelling of the lining if the joint
  • Ankylosing arthritis- arthritis that affects the spine
  • Juvenile Rheumatoid arthritis- arthritis that affects children 2 years and older

Celecoxib is also prescribed by doctors for the relief of short term (less than 7 days) pain due to surgery, injuries and other medical and dental procedures. It prevents the formation and the reduction of polyps size of patients with familial adenomatous polyposis (FAP). It helps relief acute pain due to primary dysmenorrhea or menstrual cramps.

Celecoxib works by blocking the enzyme that produces prostaglandin. This enzyme is responsible for the inflammation, pain and swelling. Compared with other NSAID drug, Celecoxib causes less ulceration of the stomach and less inflammation. It does not cause the blood to clot. However, this drug can only treat the symptoms. It will not cure the underlying conditions.

How to use Celecoxib?

Celecoxib comes in a tablet form that you need to take orally. Take this drug exactly as directed.

  • Osteoarthritis –the usual recommended dose is 100mg to times a day or 200mg once a day
  • Rheumatoid arthritis- the usual recommended dose is 200mg two times a day
  • Menstrual cramps- a single dose of 400mg on the first day followed by 200 mg if needed.
  • FAP- the usual recommended dose is 400mg two times a day
  • Ankylosing arthritis- the dose is 200mg a day or 100mg twice a day
  • Moderate to severe pain- the dose is 400mg on the first day followed by 200mg once a day.

Take Celecoxib with or without food. Do not take more than what is recommended.

What are the side effects of Celecoxib?

Some of the side effects of Celecoxib are:

  • Heartburn
  • Dizziness
  • Nausea
  • Sleepiness

Serious side effects are:

  • Hearing changes
  • Confusion
  • Blurred vision
  • Fatigue
  • Allergic reaction
  • Signs of lung inflammation such as a dry cough and tiredness
  • Signs of depression like poor concentration and changes in sleep pattern
  • Swelling of the feet and legs

Important Information

  • Celecoxib can cause a decrease in the blood counts. Tell your doctor if you have blood-related medical conditions.
  • Celecoxib is an NSAID that can cause fertility problems.
  • This medication may interact with other drugs. Tell your doctor if you are taking any other medications including vitamin and herbal supplements.
  • NSAIDs can reduce blood pressure.

Treating Pain and Stiffness due to Osteoarthritis in the Knee

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Osteoarthritis is one of the common conditions in most of the older people. Other words to describe the condition are,

  1. Degenerative joint disease.
  2. Wear-and-tear arthritis.

There is a protective tissue layer at the ends of bones that form joint. In older people, this layer degenerate. This causes the bones in the joints to rub with each other. Rubbing of bones causes pain, stiffness and other symptoms. It can occur in the adult of any age.

Sodium Hyaluronate is useful for the treatment of pain and stiffness in osteoarthritis in the knee.

How does Sodium Hyaluronate work?

Sodium Hyaluronate is an essential component of synovial fluid. It plays an important role as a tissue lubricant between adjacent tissues. It is a visco-elastic solution. The drugs replace natural lubricating substance in the body. This provides significant pain relief from the above symptoms of the joint pain. The drug helps to elements friction between the joint. This helps to reduce joint pain.

How to take Sodium Hyaluronate?

Above drug is available in the form of syringes of 20 mg (1%). A single course of treatment contains 3 injections of above drug. The doctor inject the syringe into your knee joint.

Dosage:

  • Take the injection one time in a week for 3-5 weeks.

Comments:

  • Avoid activities like jogging or other sports for at least 48 hours.
  • Avoid standing for a long time.
  • Remove joint effusion, if present.
  • Open and use the syringe at the same time.
  • Use a separate syringe to treat the other knee.
  • It is a single-use syringe.

What are the uses of Sodium Hyaluronate?

  1. Treat knee pain caused by Osteoarthritis. Above drug replaces the natural substance present in the body.
  2. Provides lubrication between the layers of tissue. This eliminates friction between the tissues.
  3. Absorbs and stores moisture in large quantity.
  4. Acts as a transportation medium for the nutrient.
  5. Acts as a filter for inflammatory molecules.
  6. Makes tissues/molecules elastic and flexible within the joints.
  7. Acts as a shock absorber.
  8. Control the movement of cells and large molecules within the joint.

What are the precautions in taking sodium Hyaluronate?

Discuss certain condition prior to start with the above treatment. Inform your doctor if you have/are;

  • Allergic to above drug.
  • Allergic to bird protein, feathers, or egg products.
  • Knee joint infections.
  • Skin infections in the area surrounding the site.
  • Circulation problems in the legs.

Safety and efficacy not studied in pregnancy and breastfeeding.

Safety and efficacy not established for use in children.

Cost of Sodium Hyaluronate (Generic and Brand)

Generic medicines and Brand drug contain the same active ingredient. They show the same effect. But brand medicines are costly. They invent the drug. This needs a huge amount to spend on research and development. Further marketing, pricing, and packaging increase their cost.

Generic medications do not need to spend for above reasons. So we can sell cheap and effective Generic medicines to our customers.

*Cost of Generic Sodium Hyaluronate.

  • 5 Syringes of 20 mg (1%) costs $ 295, per unit cost is $ 59.

*Cost of Brand Hyalgan.

  • 3 syringes of 20 mg/2 ml (2 ml) Costs $ 617.76, per unit costs is $ 205.96.