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Juvenile Arthritis Symptoms Types Risk Factors Causes and Treatment

Juvenile Arthritis: Symptoms, Types, Risk Factors, Causes, and Treatment

Disease, Pain,

The most common type of Juvenile Arthritis that children suffer from is at the age of 16. Certain forms of this condition can lead to serious complications, including growth issues, joint injuries, and eye inflammation. Treatment is focused on reducing inflammation and pain, improving the eye’s function, and avoiding injuries.

What is Juvenile Arthritis?

Juvenile arthritis (JA), or pediatric rheumatic disease, is not a specific condition. It’s a broad word to define the inflammatory and rheumatic conditions that can develop among children who are younger than. The conditions affect more than 300,000 children and teens across the United States.

The majority of JA are auto-inflammatory illnesses. The immune system is designed to defend against foreign invaders, such as bacteria and viruses, which becomes misguided and releases an inflammatory chemical that attacks healthy cells and tissues. It leads to joint swelling, inflammation, and tenderness in most JA instances. However, some forms of JA are not accompanied by joint symptoms or affect only the internal organs and the skin.

Types of Juvenile Arthritis

There are many kinds of arthritis in juveniles. The classification is based on the following factors:

  • Symptoms
  • The types and number of joints are involved
  • There are certain markers in the blood

Doctors’ classification of juvenile arthritis can help predict the disease’s development.

The most common types of juvenile arthritis include:

Oligoarticular

Oligoarticular is the term used to describe a small number of joints. In this form of arthritis, only a few joints are affected at a young age. Children younger than 8 years old are more susceptible to developing it. For half of the children with oligoarticular juvenile arthritis, just one joint is typically affected by the ankle or knee. In certain cases, this type of arthritis may require just moderate treatment. For certain children, arthritis affects four or fewer larger joints.

Polyarticular

Around 30% of children with arthritis in their juvenile years have the polyarticular form. This kind of arthritis is to be more prevalent among girls than boys.

Polyarticular juvenile arthritis can affect 5 or more joints, including large joints (knees and ankles) and smaller ones (hands and feet). Most often, both sides of your body can be affected.

Psoriatic

Children who have psoriatic arthritis have arthritis as well as:

  • A skin condition that is known as Psoriasis
  • Siblings or parents with Psoriasis

They may also suffer from the appearance of a nail and a diffuse swelling of the finger or toe called dactylitis. In certain cases, only some joints are affected; in other instances, multiple joints, including large and small ones, can be affected.

Enthesitis-related Arthritis

Enthesitis-related joint arthritis is a type of juvenile arthritis typically causes inflammation of tendons, joints, and ligaments. It can even affect the spine. Children with this kind of arthritis may experience joint pain but no obvious swelling. They may also suffer from back discomfort. 

Systemic

Systemic juvenile arthritis can cause swelling, pain, and limited movement in at least one joint. Other signs include rash and inflammation in internal organs like the liver, heart, spleen, and lymph nodes. A fever of 102deg per day for two weeks or more suggests this diagnosis.

Signs and Symptoms of Juvenile Arthritis

woman holding elbows muscle pain

Symptoms can change with time. There are times when symptoms are more intense and are referred to as flares, and when symptoms improve and get better, they are referred to as Remission. These symptoms and signs are:

  • Joint pain
  • Swelling
  • Fever
  • Stiffness
  • Rash
  • Fatigue
  • Appetite loss
  • Inflammation of the eye

The trouble with everyday tasks like dressing, walking or playing

What Causes Juvenile Arthritis?

The root cause of juvenile arthritis is unclear. Like many autoimmune diseases, the individual cases could be due to a mix of genetic causes, environmental exposures, as well as the immune system of the child.

Risk Factors for Juvenile Arthritis

Juvenile arthritis develops in the adolescent and young adult years. Children from any race and ethnic background are susceptible to the illness.

It’s uncommon to have families with more than one member family develop JA. However, children with older family members with chronic arthritis are more likely to be affected. A family member who has Psoriasis is one of the risk factors for developing a form of JA.

Treatment, Management, and Prevention of Juvenile Arthritis

Girl with pony tail sitting with doctor for a checkup

A child who has juvenile arthritis needs an intervention from a pediatric Rheumatologist. The doctor specializes in helping children with arthritis and other related ailments.

The treatment for juvenile arthritis is intended to:

  • Reduce swelling
  • Continue full motion of the affected joints
  • Reduce the pain
  • Maintain the normal development of joint

The recommended medication is:

  • Naproxen is a drug used to treat muscle pain and cramps. Naproxen is part of a group of medicines known as NSAIDs. It blocks your body’s ability to produce a substance that causes fever, pain and inflammation. 
Buy Celecoxib

Cobix (Celecoxib)

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Cobix (Celecoxib) is a prescription medication. It is intended for the treatment of arthritis, spondylitis and for the management of acute pain. It is a non-steroidal anti-inflammatory drug (NSAID). It helps relieve pain, fever, swelling and tenderness due to:

  • Osteoarthritis
  • Rheumatoid arthritis
  • Juvenile rheumatoid arthritis in children 2 years of age and older

It is also used to reduce painful menstrual cramps and short-term pain due to injuries and medical procedures. It works by blocking the enzyme that makes prostaglandins. These chemicals are an important contributor to inflammation

of arthritis. Lowering the level of the enzyme reduces the swelling, pain, tenderness and inflammation of arthritis.

Why Buy Celecoxib?

Celecoxib exerts an anti-inflammatory, analgesic and antipyretic actions with low ulcerogenic potential. Cobix is a lot cheaper than its brand names available in the market. However, both the generic and the branded counterpart contains the same active ingredients. They have the same mechanism of action and safety. Unlike other NSAID, this drug does not interfere with blood clotting. It also causes less ulceration and swelling of intestine and stomach.

How to Take Celecoxib?

Celecoxib is available in different doses. Take this drug exactly as instructed. Do not take more than what is prescribed. Take this medication with a glass of water. You should take it with food to prevent stomach upset.

For acute pain and menstrual cramps

Take 400mg of Celecoxib as an initial dose. Then take 200mg only as needed or every 12 hours on the subsequent days.

Ankylosing Spondylitis

Take 200 mg once a day or in divided doses every 12 hours. You may increase your dose to 400mg a day if there is no response to the initial dose. Discontinue therapy if there is no adequate response after taking the medication for 6 weeks.

Osteoarthritis

Take 200mg of Celecoxib once a day or every 12 hours.

Juvenile Rheumatoid arthritis

Children weighing 10-25 kg must take 50 mg of this medication every 12 hours. Those weighing 25kg must take 100mg orally every 12 hours.

Things to Remember

  • Celecoxib may interact with other drugs. However, there are no severe interactions with other drugs have been reported.
  • Prolonged use of this medication with other NSAID may increase the risk of intestinal and stomach ulcers.
  • People with high blood pressure, heart failure, kidney and liver problems must take this drug with caution.
  • This drug may cause side effects. Tell your doctor if you experience serious side effects such as:
    •  severe allergic reaction
    • signs of kidney and liver problems
    • difficulty swallowing.
Buy Etoricoxib

Relieving Swelling of Joints Associated with Gout & Arthritis

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Etoricoxib gives relief from pain & inflammation. It also provides relief from swelling of joints associated with different types of gout and arthritis. Etoricoxib is a new COX-2 selective inhibitor. It is approved in 80 countries worldwide.

How  Etoricoxib (Arcoxia) Work?

As stated above it is a selective COX-2 inhibitor. It belongs to the class of drugs of painkilers called as non-steroidal anti-inflammatory drugs. (NSAIDs) – (cox-2) cyclooxygenase 2   is responsible to reduce mediators of pain and inflammation. It inhibits Prostaglandin synthesis. It blocks only COX-2 and not COX-1 like other NSAIDs drugs. COX-1 is responsible for protecting the stomach.

What is Etoricoxib (Arcoxia) used for?

Benefits of this drug is as discussed below,

  1. Reduces swelling
  2. Relieves stiffness in joints allowing to do normal activities
  3. It also treats patients suffering from swelling due to;
  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Gout
  • Relief from chronic musculoskeletal pain
  • The risk of developing ulcers on Etoricoxib is lower than with NSAIDs
  • Your doctor may prescribe it for other reason not listed in medication guide

How to take Etoricoxib (Arcoxia)?

Dosage:

  1. Osteoarthritis and chronic musculoskeletal pain – 60 mg onetime day.
  2. Rheumatoid arthritis & ankylosing spondylitis – 90 mg one time a day.
  3. Relief of gout attack is 120 mg/day.

These tabs are oral tablets available in the strength of 120 mg. you must take this drug only for the period of pain. Swallow it with a glass of water. You can take it with or without food.

What are the precautions in taking Etoricoxib (Arcoxia)?

It is important to take precaution under certain conditions.

  1. If you have heart disease doctor may prescribe you a lower close for short period.
  2. It is less common to experience below condition. But if you have these conditions contact your doctor and stop taking Etoricoxib.
  • Breathing difficulties such as wheeze or breathless
  • Any sign of allergic reactions like swelling near your mouth, face
  • Severe itchy skin rashes
  • If you pass blood or black stools, blood in vomit, or severe tummy pains
  • Take the medicine at the same time every day
  • Avoid use of the drug in patients with peptic ulcers, severe heart disease, stroke, and hypersensitivity
  1. These drugs may be harmful in pregnancy.
  2. Drink adequate fluid to avoid dehydration.
  3. Monitor blood pressure at regular intervals while taking this medication.

Cost of Etoricoxib (Arcoxia) [Generic and Brand]

Generic Etoricoxib is much cheaper as compared to brand Arcoxia. The prices differ due to the Brand name of the company packing and pricing. The price of generic medicine decreases due to the Bulk source and other cost-saving measure taken by us. But their effects remains the same as the brand ones.

Generic Etoricoxib 120 mg tablet is $ 0.8 per unit .while the cost of Arcoxia 120 mg tablet is $ 2.68 per unit. You can see the vast difference in the cost. So buy cheap Generic drugs which give equal satisfaction to brand drugs.

Treating Symptoms of Gout (Arthritis) with Colchicine

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Colchicine tablet is an oral prescription drug.  It is used to treat the symptoms of Gout which develops suddenly.  Gout is a type of arthritis that causes your joints to swell. This is due to too much uric acid in the blood.

Colchicine can treat another rare condition, Familial Mediterranean Fever (FMF). This is a condition that is passed down in families. FMF can cause inflammation in the lungs, joints and abdomen.

What condition does Colchicine treat?

Colchicine is used to treat the symptoms of gout such as:

  • Sudden pain
  • Swelling

Symptoms of Familial Mediterranean fever:

  • Chest pain
  • Fever
  • Muscle aches
  • Swollen joint
  • Swollen, tender scrotum

How does Colchicine works?

Colchicine is an anti-drug medication. It works by lessening the uric acid buildup in the blood.  It also decreases the swelling that causes pain in the affected joints. However, it does not cure gout. Colchicine will only prevent gout attacks.

Colchicine also works by decreasing amyloid A, a protein that builds up with people having FMF.

What is the dosage of Colchicine?

The recommended dose for gout is:

  • 2 mg at first sign of symptoms to be followed by 0.6 mg an hour later with a minimum dose of 1.8 mg.
  • 6 mg of Colchicine can prevent gout from flaring. It is taken once or twice a day.

For Familial Mediterranean fever (FMF)

  • 3 – 1.8 mg once a day for children ages 4-6 years old
  • 6 – 1.8 mg once a day for children ages 6-12 years old

How to take Colchicine?

Take colchicine exactly as directed by your physician. Your dose depends upon the following:

  • Your condition
  • Your age
  • Your other medical condition
  • Your reaction to the first dose

Take the medication with or without food. Colchicine works best if you take the medication at the first sign of attack.

What are the precautions in taking Colchicine?

  • Limit your alcohol intake when taking this medication.
  • Colchicine can decrease sperm production. Talk to your doctor.
  • Do not drink grapefruit juice or eat grapefruit while taking colchicine. Grapefruit can make your body unable to process colchicine well.

Colchicine comes with several warnings.

  1. Allergic reaction- Colchicine can cause allergic reaction with symptoms such as:
  • swelling of your throat
  • swelling of tongue
  • trouble breathing

Taking the drug that you are allergic with can be fatal.

  1. Pregnant women- Enough studies were made showing how this drug can affect the unborn child.
  2. Breastfeeding- It can pass into breast milk. This may cause side effects to the child.

Costs of Colchicine

The generic brand Colchicine is cheaper than the brand name Mitigare. Colchicine 0.5 mg costs $0.42 per unit price or $25.25 for 60 tabs. While the branded Mitigare 0.5 mg costs $3.18 per unit price or $190.50 for 60 tablets.

Reducing Swelling, Pain and Joint Stiffness from Arthritis

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Nabumetone is an oral anti-inflammatory prescriptive drug. It can reduce swelling, pain and joint stiffness from arthritis.

Nabumetone is non-steroidal. It works by preventing the enzyme from creating hormones that causes swelling to your body.

What Condition Does Nabumetone Treat?

Nabumetone can treat the symptoms of:

  • Osteoarthritis
  • Rheumatoid arthritis

How does Nabumetone works?

Nabumetone reduces the production of prostaglandins in your body. This chemical causes the symptoms of arthritis such as pain and swelling. The effect is observed within one hour upon intake. But it may take up to 1 week before you feel its full effect.

What is the dosage of Nabumetone?

Nabumetone oral tablet comes in 500 mg and 750 mg. The recommended initial dose is 1,000 mg once a day. You can take the medicine once a day or in two divided doses. Your doctor may slowly increase your dosage if needed. Take the dose with or without food. For chronic treatment, the lowest effective dose is advised.

How to use Nabumetone?

Use Nabumetone as directed by your doctor. You may also follow the directions on the prescription label.

  • Take the medication by mouth. Usually once or twice a day.
  • Take the medication with food to prevent stomach upset.
  • Take with a full glass of water.
  • Avoid lying down after taking the medicine.
  • Use this medication at the lowest dosage for the shortest possible time.
  • Do not increase you dose without your doctor’s knowledge.
  • Take the medication at the first sign of pain.
  • Take the missed dose as soon as you remember.
  • Do not double up the dose.

What are the precautions for Nabumetone?

Before taking Nabumetone inform your doctor if:

  • You are allergic to aspirin.
  • You have kidney problems, asthma and heart failure.
  • You are allergic to any ingredients of nabumetone.
  • You are pregnant.
  • You are breast-feeding.
  • You have trouble getting pregnant.

While taking Nabumetone:

  • Check your blood pressure regularly.
  • Before you smoke and drink alcohol talk with your doctor. Nabumetone can cause stomach bleeding.
  • Do not use Nabumetone longer than what is
  • Limit your time under the sun. This medication can make you more sensitive to sunlight.

Costs of Nabumetone

Nabumetone is cheaper than the brand name Relafen. Nabumetone 500 mg costs $0.50 per unit price or $15.00 for 30 tabs. While the branded Relafen 500 mg costs $1.32 per unit price or $84.00 for 56 tabs.