Tag Archives: Gout

Can Children Have Gout

Can Children Have Gout?

What is Gout?

Gout is a type of arthritis that occurs when uric acid builds up in the blood and causes inflammation in the joints. It’s a condition in which uric acid builds up either because of too much uric acid intake from rich foods such as seafood, red wine, and chocolate or the body’s inability to process it. Even though the condition is more common among adults, it can also affect children.

What are the Symptoms of Gout?

The signs and symptoms of gout always occur suddenly, and often at night. This includes:

  1. Intense pain in the joint. It affects the huge toe, but it can happen in any joint. The pain is likely to be most severe within four to twelve hours after it begins.
  2. Inflammation and redness. Joints become red, warm, tender, and swollen on the affected joint. If you experience sudden, intense pain in a joint, or that goes untreated, seek medical treatment so that it will not lead to worsening the pain and joints.
  3. Limited range of motion. As gout grows, you may not be able to move your joints normally.
  4. Persistent discomfort. After the most severe pain, some joint discomfort may last from a few days to weeks. Most attacks are likely to last longer and affect more joints.

What Causes Gout in Children?

This condition occurs as a result of excessive uric acid levels in the blood. Uric acid forms when the body breaks down chemical compounds called purines. These compounds exist naturally in the body and in the foods that people eat.

How Does It Affect Children?

Pediatric gout is a condition that affects children and teenagers. It is very rare in this age group and is typically the result of an underlying medical condition. The affected joints may become painful, swollen, and stiff. If your child experience sudden, intense pain in a joint, call your doctor. If this condition is left untreated, it can lead to worsening pain and joint damage. Seek medical care immediately if you have a fever and a joint is hot and inflamed, which can be a sign of infection.

What are the Factors that Trigger Gout in Children?

  • Unhealthy diet. Unhealthy foods or a diet that is rich in red meat and shellfish and drinking beverages sweetened with fruit sugar increase levels of uric acid and may lead to gout. 
  • Weight. Obesity or being overweight in children causes the body to produce more uric acid and the kidneys have a more difficult time eliminating uric acid.
  • Medical conditions. Certain diseases and conditions increase the risk of this condition. These include untreated diabetes, obesity, metabolic syndrome, and heart and kidney diseases.
  • Family history of gout. If other members of your family have had gout, you or your child is more likely to develop the disease.
  • Age and gender. Gout occurs more often in men, primarily because women tend to have lower uric acid levels. After menopause, however, women’s uric acid levels approach those of men. This factor is uncommon in children.  

Treatment for Gout

The medications available for this condition are in two types and they focus on two different problems. The first type helps reduce the inflammation and pain associated with attacks. The second type works to prevent gout complications by lowering the amount of uric acid in your blood.

Treatment for Gout in Children

newborn baby with mother and doctor

Children who have gout associated with obesity may benefit from maintaining a moderate weight through diet and regular physical activity. Health experts state that some children may need to reduce their intake of foods that are high in purines. A nutritionist or dietician can offer advice on high-purine foods to avoid. Doctors will also prescribe a specific medication for children to manage the symptoms such as pain.

Medication Used for Gout

Allopurinol. It is short acting but its major metabolite alloxanthine is a long-acting non-competitive inhibitor of uric acid synthesis. It can be taken after meals to avoid gastric irritation. Allopurinol should be cautiously used in the elderly, children, and in kidney or liver disease.

Allopurinol

Treatment Prescribed for Patients with “Gout” and “Kidney Stones”

Allopurinol is a drug used to treat a certain condition. It’s a treatment prescribed for patients with “Gout” and “Kidney Stones”. This drug reduces the production of uric acid in the body. A high level of uric acid can increase your risk to a certain condition. The following are the condition that causes your uric acid to increase. It includes:

  • Use of diuretics
  • A person with cancer/chemotherapy
  • Gout
  • Psoriasis
  • A diet high in soft drinks, beer, beef and steak
  • Having a condition of kidney stones/damage
  • A person having a treatment with dialysis

What are the uses of  Allopurinol?

Allopurinol tablet is a drug that treats several conditions. It is useful in treating the following:

  • A person with Gout
  • A person with recurrent Kidney Stones
  • A person with Calcium Oxalate Calculi with Hyperuricosuria
  • A person having a Hyperuricemia Secondary to Chemotherapy

Indication

The use of this drug is to reduce a high uric acid level. It is an effective treatment. Allopurinol may serve as long-term medication for a person who suffers severe gout seizures. This treatment is not recommended for children. This drug is not prescribed for a patient with an allergy.

How it works?

Allopurinol is a drug that belongs to “Xanthine Oxidase Inhibitors”.  This drug works to reduce the uric acid level in the body. It works to block the xanthine oxidase. It’s an enzyme which helps to produce uric acid. It prevents the condition to occur due to high uric acid level.

How much to take?      

Follow the recommended dosage prescribed by your doctor. Do not exceed the limit use of the drug. Do not use more or less of it. Follow the direction stated carefully on the label. The usual dosage of this medicine is once per day. The strength of the medicine is 100 to 200 mg.

How to take?

Allopurinol comes in a form of a tablet. You should need to take this drug by mouth. Take allopurinol as directed by your doctor. Always check the label and follow the direction carefully. Take the drug once a day with food. You may also take this drug without food. But to avoid stomach upset it is prescribed to take it with a full stomach. Swallow the drug as a whole with water. Take it the same time each day to avoid missing a dose. Do not skip a dose to see better results.

Side effects:

The following are side effects of the drug:

  • Diarrhea
  • Nausea
  • Gout flare-up
  • Skin rash
  • Depression
  • Appetite loss
  • Stomach pain
  • Joint pain
  • Dizziness

Warning and Precaution

  • Do not take this drug if you’re allergic to its ingredient.
  • Avoid an intake of alcohol. It may increase your risk to side effects.
  • If you’re pregnant do not use this drug. It will harm your baby.
  • If you’re lactating do not use this drug. It may put your baby at risk.
  • Do not stop the medicine course without consulting your doctor.

GOUT

Gout is a form of arthritis that can affect anyone. It develops in a person with a high uric acid level in the blood. It is characterized by a severe attack of pain, redness, and tenderness of joints. It mostly develops in the big toe.

The uric acid crystal that deposits in the joint causes swelling, redness, heat and pain. The symptoms may come and go but there are ways to lessen the symptoms and flares.

2 TYPES OF GOUT

  • Flares – it is when the symptoms get worse.
  • Remission – it is when no symptoms occur.

SIGNS AND SYMPTOM

A person with gout may experience symptoms such as:

  • Experiencing an intense pain.
  • Swelling in the joints on your foot.
  • Redness
  • A person may experience a burning sensation that develops in the foot.

CAUSES OF GOUT

Gout occurs when a high level of urate crystal accumulates in the joint causing intense pain and swelling. These urate crystals are formed when you have high levels of uric acid in your blood. The list of foods below is rich in uric acid:

  • Shellfish
  • Red meats
  • Organ meat
  • Seafood
  • Alcoholic beverages like beer
  • Eating food that contains high in salt

RISK FACTORS

The following are factors that increase your chances of having gout:

  • An obese person.
  • A family history of gout.
  • Having certain health issues like heart failure, diabetes etc.
  • Using a medication like diuretics and low-dose aspirin.
  • Drinking too much alcohol.
  • Eating food or drink that is high in fructose.
  • Having an improper diet. Eating foods that are rich in purines.

DIAGNOSIS

Gout can diagnose if flare symptoms occur. The following test can help diagnose gout:

  • Conducting a physical test
  • Performing a joint fluid test
  • Taking a blood test
  • X-ray Imaging
  • Having an ultrasound
  • Dual-energy CT Scan

TREATMENT OF GOUT

Medication treatment of gout involves:

  • Managing the pain of flare and preventing a future attack – It is consists of (NSAIDS) drugs such as ibuprofen, colchicine, etoricoxib and steroids.
  • Preventing future flares – by making changes to your lifestyle.
  • Blocking the production of uric acid– Consist of xanthine oxidase inhibitors
  • Removal of uric acid– Consist of uricosurics and probenecid (Probalan)

Who should diagnose and treat gout?

This disease must only be diagnosed by an expert. A doctor who specializes in treating or caring for gout patients is known as a rheumatologist. They are the one who can determine the signs.

How can I manage my gout and improve my quality of life?

The following can help you improve your life if you have gout:

  • Eating a healthy food and maintaining a healthy diet.
  • Do not eat foods that are high in uric acid and fructose.
  • Perform a regular exercise which suits you.
  • Participate in a physical activity program.
  • Join a self-management education class.
Buy Etoricoxib

Relieving Swelling of Joints Associated with Gout & Arthritis

Etoricoxib gives relief from pain & inflammation. It also provides relief from swelling of joints associated with different types of gout and arthritis. Etoricoxib is a new COX-2 selective inhibitor. It is approved in 80 countries worldwide.

How  Etoricoxib (Arcoxia) Work?

As stated above it is a selective COX-2 inhibitor. It belongs to the class of drugs of painkilers called as non-steroidal anti-inflammatory drugs. (NSAIDs) – (cox-2) cyclooxygenase 2   is responsible to reduce mediators of pain and inflammation. It inhibits Prostaglandin synthesis. It blocks only COX-2 and not COX-1 like other NSAIDs drugs. COX-1 is responsible for protecting the stomach.

What is Etoricoxib (Arcoxia) used for?

Benefits of this drug is as discussed below,

  1. Reduces swelling
  2. Relieves stiffness in joints allowing to do normal activities
  3. It also treats patients suffering from swelling due to;
  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Gout
  • Relief from chronic musculoskeletal pain
  • The risk of developing ulcers on Etoricoxib is lower than with NSAIDs
  • Your doctor may prescribe it for other reason not listed in medication guide

How to take Etoricoxib (Arcoxia)?

Dosage:

  1. Osteoarthritis and chronic musculoskeletal pain – 60 mg onetime day.
  2. Rheumatoid arthritis & ankylosing spondylitis – 90 mg one time a day.
  3. Relief of gout attack is 120 mg/day.

These tabs are oral tablets available in the strength of 120 mg. you must take this drug only for the period of pain. Swallow it with a glass of water. You can take it with or without food.

What are the precautions in taking Etoricoxib (Arcoxia)?

It is important to take precaution under certain conditions.

  1. If you have heart disease doctor may prescribe you a lower close for short period.
  2. It is less common to experience below condition. But if you have these conditions contact your doctor and stop taking Etoricoxib.
  • Breathing difficulties such as wheeze or breathless
  • Any sign of allergic reactions like swelling near your mouth, face
  • Severe itchy skin rashes
  • If you pass blood or black stools, blood in vomit, or severe tummy pains
  • Take the medicine at the same time every day
  • Avoid use of the drug in patients with peptic ulcers, severe heart disease, stroke, and hypersensitivity
  1. These drugs may be harmful in pregnancy.
  2. Drink adequate fluid to avoid dehydration.
  3. Monitor blood pressure at regular intervals while taking this medication.

Cost of Etoricoxib (Arcoxia) [Generic and Brand]

Generic Etoricoxib is much cheaper as compared to brand Arcoxia. The prices differ due to the Brand name of the company packing and pricing. The price of generic medicine decreases due to the Bulk source and other cost-saving measure taken by us. But their effects remains the same as the brand ones.

Generic Etoricoxib 120 mg tablet is $ 0.8 per unit .while the cost of Arcoxia 120 mg tablet is $ 2.68 per unit. You can see the vast difference in the cost. So buy cheap Generic drugs which give equal satisfaction to brand drugs.

Treating Symptoms of Gout (Arthritis) with Colchicine

Colchicine tablet is an oral prescription drug.  It is used to treat the symptoms of Gout which develops suddenly.  Gout is a type of arthritis that causes your joints to swell. This is due to too much uric acid in the blood.

Colchicine can treat another rare condition, Familial Mediterranean Fever (FMF). This is a condition that is passed down in families. FMF can cause inflammation in the lungs, joints and abdomen.

What condition does Colchicine treat?

Colchicine is used to treat the symptoms of gout such as:

  • Sudden pain
  • Swelling

Symptoms of Familial Mediterranean fever:

  • Chest pain
  • Fever
  • Muscle aches
  • Swollen joint
  • Swollen, tender scrotum

How does Colchicine works?

Colchicine is an anti-drug medication. It works by lessening the uric acid buildup in the blood.  It also decreases the swelling that causes pain in the affected joints. However, it does not cure gout. Colchicine will only prevent gout attacks.

Colchicine also works by decreasing amyloid A, a protein that builds up with people having FMF.

What is the dosage of Colchicine?

The recommended dose for gout is:

  • 2 mg at first sign of symptoms to be followed by 0.6 mg an hour later with a minimum dose of 1.8 mg.
  • 6 mg of Colchicine can prevent gout from flaring. It is taken once or twice a day.

For Familial Mediterranean fever (FMF)

  • 3 – 1.8 mg once a day for children ages 4-6 years old
  • 6 – 1.8 mg once a day for children ages 6-12 years old

How to take Colchicine?

Take colchicine exactly as directed by your physician. Your dose depends upon the following:

  • Your condition
  • Your age
  • Your other medical condition
  • Your reaction to the first dose

Take the medication with or without food. Colchicine works best if you take the medication at the first sign of attack.

What are the precautions in taking Colchicine?

  • Limit your alcohol intake when taking this medication.
  • Colchicine can decrease sperm production. Talk to your doctor.
  • Do not drink grapefruit juice or eat grapefruit while taking colchicine. Grapefruit can make your body unable to process colchicine well.

Colchicine comes with several warnings.

  1. Allergic reaction- Colchicine can cause allergic reaction with symptoms such as:
  • swelling of your throat
  • swelling of tongue
  • trouble breathing

Taking the drug that you are allergic with can be fatal.

  1. Pregnant women- Enough studies were made showing how this drug can affect the unborn child.
  2. Breastfeeding- It can pass into breast milk. This may cause side effects to the child.

Costs of Colchicine

The generic brand Colchicine is cheaper than the brand name Mitigare. Colchicine 0.5 mg costs $0.42 per unit price or $25.25 for 60 tabs. While the branded Mitigare 0.5 mg costs $3.18 per unit price or $190.50 for 60 tablets.