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Can Children Have Gout

Can Children Have Gout?

What is Gout?

Gout is a type of arthritis that occurs when uric acid builds up in the blood and causes inflammation in the joints. It’s a condition in which uric acid builds up either because of too much uric acid intake from rich foods such as seafood, red wine, and chocolate or the body’s inability to process it. Even though the condition is more common among adults, it can also affect children.

What are the Symptoms of Gout?

The signs and symptoms of gout always occur suddenly, and often at night. This includes:

  1. Intense pain in the joint. It affects the huge toe, but it can happen in any joint. The pain is likely to be most severe within four to twelve hours after it begins.
  2. Inflammation and redness. Joints become red, warm, tender, and swollen on the affected joint. If you experience sudden, intense pain in a joint, or that goes untreated, seek medical treatment so that it will not lead to worsening the pain and joints.
  3. Limited range of motion. As gout grows, you may not be able to move your joints normally.
  4. Persistent discomfort. After the most severe pain, some joint discomfort may last from a few days to weeks. Most attacks are likely to last longer and affect more joints.

What Causes Gout in Children?

This condition occurs as a result of excessive uric acid levels in the blood. Uric acid forms when the body breaks down chemical compounds called purines. These compounds exist naturally in the body and in the foods that people eat.

How Does It Affect Children?

Pediatric gout is a condition that affects children and teenagers. It is very rare in this age group and is typically the result of an underlying medical condition. The affected joints may become painful, swollen, and stiff. If your child experience sudden, intense pain in a joint, call your doctor. If this condition is left untreated, it can lead to worsening pain and joint damage. Seek medical care immediately if you have a fever and a joint is hot and inflamed, which can be a sign of infection.

What are the Factors that Trigger Gout in Children?

  • Unhealthy diet. Unhealthy foods or a diet that is rich in red meat and shellfish and drinking beverages sweetened with fruit sugar increase levels of uric acid and may lead to gout. 
  • Weight. Obesity or being overweight in children causes the body to produce more uric acid and the kidneys have a more difficult time eliminating uric acid.
  • Medical conditions. Certain diseases and conditions increase the risk of this condition. These include untreated diabetes, obesity, metabolic syndrome, and heart and kidney diseases.
  • Family history of gout. If other members of your family have had gout, you or your child is more likely to develop the disease.
  • Age and gender. Gout occurs more often in men, primarily because women tend to have lower uric acid levels. After menopause, however, women’s uric acid levels approach those of men. This factor is uncommon in children.  

Treatment for Gout

The medications available for this condition are in two types and they focus on two different problems. The first type helps reduce the inflammation and pain associated with attacks. The second type works to prevent gout complications by lowering the amount of uric acid in your blood.

Treatment for Gout in Children

newborn baby with mother and doctor

Children who have gout associated with obesity may benefit from maintaining a moderate weight through diet and regular physical activity. Health experts state that some children may need to reduce their intake of foods that are high in purines. A nutritionist or dietician can offer advice on high-purine foods to avoid. Doctors will also prescribe a specific medication for children to manage the symptoms such as pain.

Medication Used for Gout

Allopurinol. It is short acting but its major metabolite alloxanthine is a long-acting non-competitive inhibitor of uric acid synthesis. It can be taken after meals to avoid gastric irritation. Allopurinol should be cautiously used in the elderly, children, and in kidney or liver disease.

Buy Colchicine

Colchicine for Treating Familial Mediterranean Fever

Colchicine is a prescription medication available as a brand name and generic version. It is prescribed for the prevention and treatment of swelling and joint pain due to gout and Familial Mediterranean fever. It’s a second-choice treatment for a gout attack, an alternative for those who are unable to tolerate NSAIDs in gout. It’s more popular than other colchicum alkaloids.

Colchicine is an alkaloid derivative from the dried seeds of Colchicum autumnale or also known as autumn crocus. It was approved by the US FDA for medical use since 1961 and has been one of the most prescribed medications in the US.

What condition does Colchicine treat?

Colchicine Knee Pain

Colchicine is used for:

  • Preventing gout attacks in people who are starting with long-term preventive treatment medication such as allopurinol, sulfinpyrazone, or febuxostat.
  • Relieving of pain due to an acute gout attack particularly to those who can’t take anti-inflammatory painkillers like NSAIDs.
  • Treatment of familial Mediterranean fever, an inborn condition that causes pain, fever, and swelling of the lungs, stomach area, and joints in both adults and children aged 4 years and older.
  • Long-term treatment and management of Behcet’s disease, a type of inflammatory disorder that affects multiple parts of the body.
  • A part of therapy for conditions like pericarditis, pulmonary fibrosis, scleroderma, and biliary cirrhosis.
  • Reduce attack and long-term risk of amyloidosis.
  • Prevention of atrial fibrillation after cardiac surgery

How does Colchicine work?

  • Colchicine is an anti-gout medication. People often experience gout due to the uric acid-forming painful crystals in the body, mostly in the joint.
  • Neutrophil, a type of white blood cells, migrates and engulfs the uric acid crystals in the joint causing inflammatory enzymes and lactic acid to be released. These tempers pain and inflammatory responses.
  • Colchicine stops the action of a neutrophil by binding with the white blood cells. As a result, the cells are unable to move to certain joints in the body where uric acid crystals are formed, thus, reducing the pain and inflammation in the joint.

What is the dosage of Colchicine?

Colchicine comes in a tablet form for you to take orally.

  • Gout flares: The initial recommended dose is one tablet 1 to 3 times a day until the pain eases. Take 1.2 mg at the first sign of gout flares. Take another 0.6mg one hour after.
  • Gout flares prevention: The typical dose in preventing gout flares is 0.6mg once or twice daily. If you have taken an extra dose after a recurring gout attack, do not take another dose until at least 12 hours have passed.
  • Familial Mediterranean fever: The recommended dose for an adult is 1.2 to 2.4 mg once a day. The dose for children aged 12 to 15 is 1.2mg to 2.4mg a day. The dose for children aged 6 to 11 is 0.9 to 1.8mg a day while the dose for children aged 4 to 5 years is 0.3 to 1.8mg a day.

How to take Colchicine?

  • You can only take it after you experience two or more gout attacks per year.
  • Do not take more than 12 tablets as a course of treatment during any one gout attack. Leave at least three days between each course.
  • The onset of effect can be observed in 18 to 24 hours while the duration of the effect lasts for an average of 6 to 30 hours.
  • Take colchicine exactly as directed. Follow the directions on the prescription label. Do not take more or less than what is prescribed or for longer than the duration of treatment. It comes with risk if you will not take it as prescribed. Taking too much can cause serious problems.
  • If you do not experience relief or have a gout attack during the duration of your treatment, call your doctor right away.

What are the precautions in taking Colchicine?

  • Do not take Colchicine if:
    • You have disturbances in the normal numbers of blood cells
    • You are pregnant or breastfeeding
    • You have severe kidney or liver disease
  • Extra monitoring and a lower dose are needed if:
    • You have heart disease
    • You have kidney or liver problems
    • Elderly people
    • You have stomach or intestinal problems
  • Colchicine is not a pain reliever medication. It should not be used in treating pain that is not caused by gout or Familial Mediterranean fever. The anti-inflammatory properties are potent but its effectiveness in treating other pain associated conditions is limited.
  • This medicine won’t alter the high uric acid levels among patients with gout.
  • Colchicine can lower your body’s ability to make new blood cells even if you are taking it correctly. If you are experiencing frequent bleeding, fever, bruising and you always feel tired contact your doctor as soon as possible. At a low dose, this medicine is well-tolerated. A higher dose can be effective against pain but can cause severe side effects like nausea, vomiting, and diarrhea.
  • Colchicine can control Familial Mediterranean fever and gout attacks only as long as you take them. Continue taking your medication even if you feel well.
  • Your doctor may prescribe you other medications if you are experiencing frequent gout attacks.
  • There are certain lifestyle changes that you can make to help reduce the risk of having gout attacks. These include having a healthy diet, avoiding alcohol and soft drinks.
  • Medicines can cause unusual effects aside from their intended effects. Common side effects are nausea, diarrhea, and pain in the abdomen. If you will experience any other side effects, stop taking your medication and call your doctor right away.

Costs of Generic Colchicine vs. Colcrys

Colchicine is an inexpensive anti-gout medication. It’s cheaper than the brand name Colcrys. Colchicine 0.5mg cost $0.36 per unit price or $65.18 for 180 tabs. While the brand name Colcrys cost $58.43 for 30 tabs or $1.94 per unit price.