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Treating Pain and Stiffness due to Osteoarthritis in the Knee

Osteoarthritis is one of the common conditions in most of the older people. Other words to describe the condition are,

  1. Degenerative joint disease.
  2. Wear-and-tear arthritis.

There is a protective tissue layer at the ends of bones that form joint. In older people, this layer degenerate. This causes the bones in the joints to rub with each other. Rubbing of bones causes pain, stiffness and other symptoms. It can occur in the adult of any age.

Sodium Hyaluronate is useful for the treatment of pain and stiffness in osteoarthritis in the knee.

How does Sodium Hyaluronate work?

Sodium Hyaluronate is an essential component of synovial fluid. It plays an important role as a tissue lubricant between adjacent tissues. It is a visco-elastic solution. The drugs replace natural lubricating substance in the body. This provides significant pain relief from the above symptoms of the joint pain. The drug helps to elements friction between the joint. This helps to reduce joint pain.

How to take Sodium Hyaluronate?

Above drug is available in the form of syringes of 20 mg (1%). A single course of treatment contains 3 injections of above drug. The doctor inject the syringe into your knee joint.


  • Take the injection one time in a week for 3-5 weeks.


  • Avoid activities like jogging or other sports for at least 48 hours.
  • Avoid standing for a long time.
  • Remove joint effusion, if present.
  • Open and use the syringe at the same time.
  • Use a separate syringe to treat the other knee.
  • It is a single-use syringe.

What are the uses of Sodium Hyaluronate?

  1. Treat knee pain caused by Osteoarthritis. Above drug replaces the natural substance present in the body.
  2. Provides lubrication between the layers of tissue. This eliminates friction between the tissues.
  3. Absorbs and stores moisture in large quantity.
  4. Acts as a transportation medium for the nutrient.
  5. Acts as a filter for inflammatory molecules.
  6. Makes tissues/molecules elastic and flexible within the joints.
  7. Acts as a shock absorber.
  8. Control the movement of cells and large molecules within the joint.

What are the precautions in taking sodium Hyaluronate?

Discuss certain condition prior to start with the above treatment. Inform your doctor if you have/are;

  • Allergic to above drug.
  • Allergic to bird protein, feathers, or egg products.
  • Knee joint infections.
  • Skin infections in the area surrounding the site.
  • Circulation problems in the legs.

Safety and efficacy not studied in pregnancy and breastfeeding.

Safety and efficacy not established for use in children.

Cost of Sodium Hyaluronate (Generic and Brand)

Generic medicines and Brand drug contain the same active ingredient. They show the same effect. But brand medicines are costly. They invent the drug. This needs a huge amount to spend on research and development. Further marketing, pricing, and packaging increase their cost.

Generic medications do not need to spend for above reasons. So we can sell cheap and effective Generic medicines to our customers.

*Cost of Generic Sodium Hyaluronate.

  • 5 Syringes of 20 mg (1%) costs $ 295, per unit cost is $ 59.

*Cost of Brand Hyalgan.

  • 3 syringes of 20 mg/2 ml (2 ml) Costs $ 617.76, per unit costs is $ 205.96.