Tag Archives: celecoxib

Kidney Infection

Kidney Infection

Kidney Infection is a serious infection that needs to treat right away. When bacteria or viruses get into your kidneys, usually through your urinary tract, they can cause a kidney infection. If a kidney infection is not treated, it can get worse and sometimes cause permanent kidney damage. 

What Causes Kidney Infection?

The viruses or bacteria that cause kidney infections usually come from another part of your urinary tract, such as your bladder, ureters, or urethra, and spread to your kidneys. Less commonly, the viruses or bacteria come from an infection elsewhere in your body. 

Kidney infection can also happen if the flow of urine through your urinary tract is blocked. This can happen because of:

  • An enlarged prostate
  • Kidney stones
  • A problem with the shape of your urinary tract that makes it harder for urine to pass through

What Are The Symptoms Of Kidney Infection?

Diarrhea

Symptoms of a kidney infection may include:

  • Feeling sick to your stomach 
  • Throwing up
  • Chills
  • Fever
  • Diarrhea
  • Urine that is cloudy or smells bad
  • Blood or pus in your urine
  • Pain or burning when urinating
  • Feeling like you have to urinate even if you just went
  • Urinating more often than normal
  • Pain in your lower back, one or both sides of your groin

If you notice any of these symptoms, call your doctor right away. If you are currently taking medication for the treatment of urinary tract infection, but you are still having any of these symptoms, call your doctor.  

How to Diagnose Kidney Infection?

To know if you have a kidney infection, doctors may do tests such as:

  • Blood tests
  • Urine tests to look for bacteria or other signs of infection, such as white blood cells, in your urine
  • Imaging tests to look at your kidneys, such as a CT scan, X-ray, or ultrasound.
  • For men, a rectal exam is recommended. It is where the doctor inserts a gloved, lubricated finger into the anus to see if the prostate gland is enlarged and blocks the flow of urine.

How to Treat Kidney Infection?

Doctors treat most kidney infections with antibiotics. Doctors will prescribe an antibiotic medicine based on:

  • What type of bacteria is causing the infection
  • If you are older than 65
  • How severe the infection is
  • If you are you are pregnant
  • If you had problems from certain antibiotics in the past, such as allergic reactions

If you have a very serious infection, you may need to stay in the hospital to get antibiotics through an IV. You may also get pain medicine.

Medications Used For Kidney Infection

What Are The Medications Used For Kidney Infection?

1. Antibiotics

2. Pain Killers 

It is very important to get medical treatment for kidney infections as soon as possible. You should not wait for it to go away on its own. Kidney infections that are not treated soon enough can cause permanent kidney damage or can spread to other parts of your body. 

Celecoxib Treats Different Types of Pain and Inflammation

Celecoxib Treats Different Types of Pain and Inflammation

Celecoxib is a generic drug sold under the brand name Celebrex. It is a pain medicine. It treats different types of pain and inflammation. It reduces pain in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. It is effective in painful menstruation, pain in adults. It is helpful in juvenile arthritis in people two years or older. It belongs to class of NSAID drugs and sub group COX-2 inhibitors.

CREDIBILITY:

It treats arthritis and is marketed by Pfizer. It is sold only by prescription in the form of capsule. It was one of the best-selling drug by 2012. As of 2015, the cost for a typical month of medication in US was more than $200. As of 2017, the cost of generic version of Celecoxib was nearly $30. It is in market for over 17 years. Celebrex is approved by FDA. Teva pharmaceutical industries got the permission from FDA to market cheaper generic version of celecoxib capsule in 50, 100, 200, 400 mg On Friday, May 30 2014 ( so the generic is relatively new )

WORKING:

It gives relief from pain and discomfort due to various disease as described above. During inflammation body make prostaglandin that may cause pain. Celecoxib decreases the production of prostaglandin. This reduces the body pain. Thus giving  relief from pain and swelling.

DOSAGES:

It is available in capsule form in the following strength 50 mg, 100 mg, 200 mg, and 400 mg.

It is to swallow along with water or any other liquid. Take it with food to avoid an upset stomach.  Standard dose is as follows;

  1. 100 mg – two times every day
  2. 200 mg – one time every day
  3. 400 mg – as a single dose on the first day and 200 mg two times on the following days. Take it at least five days. Available only on doctor’s prescription.

ADVANTAGES:

  1. It is useful for relieving pain in osteoarthritis, rheumatoid arthritis.
  2. It is effective in case of acute pain in adult musculoskeletal pain.
  3. Shows good result in ankylosing spondylitis and juvenile arthritis on people two years or older.
  4. It is effective same as ibuprofen in case of pain after surgery.
  5. Action is similar to paracetamol
  6. It is considered as first line treatment in osteoarthritis
  7. Evidences indicate its use in treating a number of psychiatric disorders.
  8. It gives comfort in other short term pain and menstruation cramps.

SIDE EFFECTS:

Common side effects include;

  1. Nausea
  2. Diarrhea
  3. Stomach upset
  4. Abdominal pain
  5. Headache
  6. Dizziness
  7. Nervousness
  8. Skin rashes
  9. Stuff nose
  10. Some other major side effects may be stomach and intestinal ulcer
  11. Chest pain, shortness of breath,
  12. Slurred speech,
  13. Loss appetite,
  14. Dark urine,
  15. Jaundice,

But these are rare cases .Call doctor if such major side effects occur.

PRECAUTIONS:

It is necessary to take precaution in certain cases as discussed below

  1. It belong to class of NSAID drugs. It can increase your risk of heart attack or other heart disease.
  2. Patients with heart surgery should not use it.
  3. If you are 65+ you may be at a risk of stomach bleeding, ulcer in the lining of stomach or intestine
  4. Avoid taking it if you are an asthmatic patient.
  5. Do not take in late pregnancy and during breast feeding
  6. Check if patient takes any other NSAID drugs as it can interact with them

Cost of Celecoxib VS Celebrex:

Generic drugs are cheaper than brand named drugs and have the  same effect. They both contain the same active ingredient. Celebrex is costly because it’s a  brand name and was not available as generic form until 2014. It used to cost about $100 to $500 per month. Each pill cost $ 2. Single pill by Cheap drugs in Canada cost $3.30. Quality prescription drugs in USA cost $1.75. While the cost of generic Celecoxib is just $ 0.22 per pill. One can see the gargantuan difference in price – its sky high.

The above information clearly shows how effective is generic Celecoxib as compared to Celebrex . It is as effective and much …much more affordable.

Buy Celecoxib

Medication To Treat Osteoarthritis, Rheumatoid , Ankylosing, Juvenile Rheumatoid Arthritis

Celecoxib is a prescription anti-inflammatory medication. It belongs to the group of drug known as selective COX-2 inhibitors, a kind of non-steroidal anti-inflammatory drug (NSAID). It is prescribed for the treatment of conditions like:

  • Osteoarthritis –caused by the breakdown of the lining of the joints
  • Rheumatoid arthritis- swelling of the lining if the joint
  • Ankylosing arthritis- arthritis that affects the spine
  • Juvenile Rheumatoid arthritis- arthritis that affects children 2 years and older

Celecoxib is also prescribed by doctors for the relief of short term (less than 7 days) pain due to surgery, injuries and other medical and dental procedures. It prevents the formation and the reduction of polyps size of patients with familial adenomatous polyposis (FAP). It helps relief acute pain due to primary dysmenorrhea or menstrual cramps.

Celecoxib works by blocking the enzyme that produces prostaglandin. This enzyme is responsible for the inflammation, pain and swelling. Compared with other NSAID drug, Celecoxib causes less ulceration of the stomach and less inflammation. It does not cause the blood to clot. However, this drug can only treat the symptoms. It will not cure the underlying conditions.

How to use Celecoxib?

Celecoxib comes in a tablet form that you need to take orally. Take this drug exactly as directed.

  • Osteoarthritis –the usual recommended dose is 100mg to times a day or 200mg once a day
  • Rheumatoid arthritis- the usual recommended dose is 200mg two times a day
  • Menstrual cramps- a single dose of 400mg on the first day followed by 200 mg if needed.
  • FAP- the usual recommended dose is 400mg two times a day
  • Ankylosing arthritis- the dose is 200mg a day or 100mg twice a day
  • Moderate to severe pain- the dose is 400mg on the first day followed by 200mg once a day.

Take Celecoxib with or without food. Do not take more than what is recommended.

What are the side effects of Celecoxib?

Some of the side effects of Celecoxib are:

  • Heartburn
  • Dizziness
  • Nausea
  • Sleepiness

Serious side effects are:

  • Hearing changes
  • Confusion
  • Blurred vision
  • Fatigue
  • Allergic reaction
  • Signs of lung inflammation such as a dry cough and tiredness
  • Signs of depression like poor concentration and changes in sleep pattern
  • Swelling of the feet and legs

Important Information

  • Celecoxib can cause a decrease in the blood counts. Tell your doctor if you have blood-related medical conditions.
  • Celecoxib is an NSAID that can cause fertility problems.
  • This medication may interact with other drugs. Tell your doctor if you are taking any other medications including vitamin and herbal supplements.
  • NSAIDs can reduce blood pressure.