Tag Archives: Angina Pectoris

Angina Pectoris

Angina Pectoris

Disease, health and medicine, , ,

Angina Pectoris is chest pain or discomfort that keeps coming back. It happens when some part of your heart does not get enough blood and oxygen. Angina can be a symptom of coronary artery disease which occurs when arteries that carry blood to your heart become narrowed and blocked because of blood clots or atherosclerosis. It can also occur because of poor blood flow through a narrowed heart valve, unstable plaques, a reduced pumping function of the heart muscle, as well as a coronary artery spasm.

There are two other forms of angina pectoris:

  • Variant angina pectoris 
  • Microvascular angina 
Angina

Causes of Angina Pectoris

Angina is caused by decreased blood flow to your heart muscle. Your blood carries oxygen which your heart muscle needs to survive. Once your heart is not getting enough oxygen, it causes a condition called ischemia. 

During times of low oxygen demand, your heart muscle may still be able to function on the decreased amount of blood flow without triggering angina symptoms. 

Risk Factors of Angina Pectoris

The following risk factors increase your risk of angina:

  • Diabetes
  • Tobacco use
  • High blood cholesterol or triglyceride levels
  • High blood pressure 
  • Older age
  • Family history of heart disease
  • Stress
  • Obesity
  • Lack of exercise 

Symptoms of Angina Pectoris

Angina symptoms may include chest discomfort and pain. You may also have pain in your back, shoulder, jaw, neck, or arms. 

Other symptoms that you may have include:

These symptoms need to be assessed right away by a doctor who can determine whether you have stable angina which can be a precursor to a heart attack.

Diagnosis

Diagnosis of Angina Pectoris

To diagnose angina, your doctor will start by doing a physical exam and asking about your symptoms. You will also be asked about any risk factors, including whether you have a family history of heart disease.  

There are other tests that your doctor may help to confirm whether you have angina:

  • Electrocardiogram
  • Stress test
  • Echocardiogram
  • Nuclear stress test
  • Chest X-ray
  • Blood tests
  • Coronary angiography
  • Cardiac computerized tomography scan
  • Cardiac MRI

Treatment and Medications for Angina Pectoris

There are lots of treatment options for angina pectoris including medications, lifestyle changes, coronary bypass surgery, or angioplasty and stenting. The goal of the treatment is to lessen the frequency and severity of a heart attack. However, if you have unstable angina or angina pain that is different from what you usually have, you need immediate treatment. 

If lifestyle changes alone don’t help your angina, you may need to take medications such as:

  • Nitrates 
  • Aspirin
  • Beta-blockers
  • Statins
  • Calcium channel blockers
  • Blood pressure-lowering medications 
  • Clot-preventing drugs – Clopidogrel helps prevent blood clots from forming by making your blood platelets less likely to stick together.  

Buy Nifedipine

Nifedipine

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Nifedipine is a prescription calcium channel blocker used for:

  • Lowering the blood pressure
  • Prevention of rapid heart rhythm episodes
  • Preventing angina pectoris or chest pain attack due to an increased workload of the heart or spasm of the coronary arteries

The short-acting tablet is used for:

  • Treating Raynaud’s phenomenon, a condition where the blood vessels in the feet and hands go into spasm causing numbness, white and painful toes and fingers.
  • Treating hiccups in palliative care

Non-FDA approved uses include:

  • Postponing premature labor (off-label)
  • Prevention of migraine headaches in adults
  • Anal fissure
  • Wound healing
  • Ureteral stones as secondary therapy

Nifedipine is mainly prescribed for the treatment of hypertension or high blood pressure. It’s a common condition but its long-term effect can cause serious medical conditions like heart problems and even death. Untreated high blood pressure can cause damages to the heart, blood vessels, kidneys and other organs of the body. Damages to these organs may cause heart disease, heart failure, heart attack, stroke, loss of vision, kidney failure and other problems. High blood pressure happens when blood pressure increases to an unhealthy level. You can get high blood pressure for years without any symptoms. It generally develops over years and affects nearly everyone. Fortunately, most high blood pressure can easily be detected.

It’s also used to treat two types of angina pectoris or chest pain: chronic stable angina and vasospastic angina.  Angina pectoris is a type of chest discomfort due to coronary heart disease. It usually happens when one or more of the heart’s arteries is blocked or narrowed due to insufficient oxygen that it gets.

Nifedipine blocks the calcium channel found on the muscle cells in the walls of the arteries. This causes the walls to relax and widens. Relaxing the walls of the arteries reduces the resistance of the heart to pump blood around the body. This in return reduces the pressure in the blood vessels. Nifedipine helps control high blood pressure along with making a lifestyle change. These changes include maintaining a healthy weight, eating a diet that is low in salt and fat, exercising at least 30 minutes a day, using alcohol in moderation and not smoking.

Nifedipine also helps relax the peripheral arteries in the hands and feet which improve the circulation of blood in the fingers and toes. This helps relieve the symptoms of Raynaud’s phenomenon. 

Why Buy Nifedipine?

Nifedipine is a potent calcium channel blocker that’s approved by the Food and Drug Administration for medical use in the United State since 1981. It’s listed as one of the safest and most effective medicines needed in the health system. It’s a generic medicine that works well in lowering the blood pressure and in preventing chest pain. It’s a first-choice treatment for high blood pressure and Prinzmetal angina for many people. Nifedipine prevents heart attack, stroke and heart-related chest pain when used regularly. Nifedipine is also available in several brand names in the market. However, the brand names cost much than the generic version.

How to Take Nifedipine?

Your dose and the duration of your treatment depend on your condition. The typical recommended dose for treating angina pectoris is 10 mg to 20 mg three times a day. The maximum recommended dose is 180 mg a day. For hypertension, take 30 mg to 60 mg a day. Nifedipine comes in a tablet and capsule form for you to take by mouth. You can take it with or without food. Swallow the tablet whole with water.

The short-acting capsule takes effect as soon as the medicine is absorbed by the body and then tapers off. So you should take it three times a day. The long-acting tablet and capsule release the medicine steadily over the day. You need to take it once or two times a day.

What are the possible side effects of Nifedipine?

Nifedipine may cause unwanted side effects like any other medications and these may affect individuals in different ways. Contact your doctor right away if you have serious side effects like:

  • Fainting
  • Pounding or fast heartbeats
  • Short breath
  • Low blood pressure
  • Swollen ankles due to fluid retention
  • Swelling in the hands or feet
  • numbness or tingly feeling
  • Worsening angina
  • Yellowing of the skin or eyes
  • Chest pain, pain that spread to the arms or shoulder
  • Nausea
  • Sweating
  • General ill feeling
  • Visual disturbance

Less serious side effects are:

  • Leg cramp
  • Joint pain
  • Headache
  • Dizziness
  • Sleep problems
  • Nausea
  • Diarrhea
  • Itching, mild rashes
  • Feeling tired
  • Stomach pain
  • Constipation
  • Chills
  • Migraine
  • Nosebleed
  • Urinating more than usual

Rare side effects are:

  • Infertility in men
  • Loss of appetite
  • Enlargement of the gums

A very serious side effect is rare. However, if you will notice any serious side effects seek immediate medical attention.

Things to Remember

  • Do not miss a dose. Stopping your medication can cause your blood pressure to go up suddenly which raises your risk of stroke and heart attack.
  • Avoid grapefruit because it can make the effect of this medicine stronger.
  • Nifedipine can make you feel dizzy or weary. Avoid drinking alcoholic beverages. When getting up from sitting or lying position, do it slowly
  • In addition to taking your medication, making a lifestyle change can also control your blood pressur
  • Do not take this to treat an angina attack that has started because it won’t work quickly enough.
  • Have a regular blood sugar check-up because this medicine may affect the level of sugar in your blood.
  • Tell your doctor if you are using this medication before having surgery.
  • Do not use this if:
    • You are having an ongoing angina attack because this drug doesn’t work that quickly compared with glyceryl trinitrate (GTN).
    • You have had a recent heart attack
    • You are allergic to any of the ingredients
    • You have a liver problem, blockage in the stomach or intestines, ulcerative colitis or Crohn’s disease
  • Use in a lower dose if:
    • You are 65 years old and above
    • You have a heart failure
    • You have a severe liver problems
    • You have a diabetes
Buy Carvedilol

Carvedilol

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Carvedilol is a prescription beta blocker. It is indicated for the treatment of:

  • Angina pectoris or chest pain from the heart
  • Stable, chronic heart failure in addition to standard medicines used to treat heart failure
  • High blood pressure or hypertension

Carvedilol is also used after a heart attack to improve the chances of survival if the heart is not pumping blood well. Lowering blood pressure helps prevent heart attack, stroke, and kidney problems. Carvedilol is a beta-adrenergic blocking agent that works by blocking the receptors of the adrenergic nervous system. This prevents the nerve from releasing an adrenergic chemical known as norepinephrine that stimulates the heart muscle to beat more rapidly and forcefully. Carvedilol also blocks the receptors in the arteries causing it to relax and the blood pressure to lower.

 

Why Buy Carvedilol?

Carvedilol is an effective beta-blocker that’s FDA-approved. It’s a first-choice treatment for heart attack and heart failure. This beta blocker reduces the risk of second heart attack by 40% and increases the chances of survival of patients with congestive heart failure. Although it’s not a first-choice treatment for high blood pressure, it’s a first-choice drug for the prevention of angina pectoris.

How to Take Carvedilol?

Take Carvedilol exactly as directed. Your dose depends on your age, condition being treated and how you react to the first dose. The typical dose for an adult with heart function problem is 6.25 mg two times a day. Your doctor may increase your dose after 3 to 10 days to 12.5 mg two times a day. The maximum recommended dose is 25 mg a day.

The recommended dose for the treatment of high blood pressure is 6.25 mg twice a day. The dose may be increased after 7 to 14 days based on the blood pressure level. The maximum recommended dose is 50 mg a day.

Take it with food to reduce the risk of side effects.

Things to Remember

  • Do not stop taking your medication without informing your doctor. Stopping your medication all of a sudden can worsen your chest pain; cause your heart rhythm to change or heart attack.
  • This medication can cause a decrease in your heart rate. If this happens, talk to your doctor so your doctor may decrease your dose. It may also cause loss of consciousness due to very low blood pressure.
  • Carvedilol can make your blood sugar level low.
  • Do not use Carvedilol if you have:
    • AN uncontrolled heart failure
    • A decreased liver function
    • Chronic obstructive pulmonary disease or COPD
    • History of asthma
    • Very low blood pressure
    • Untreated tumor of the adrenal gland
  • Use with care among patients with:
    • A severe form of chest pain
    • Diabetes
    • Poor blood circulation in the artery
    • An overactive thyroid gland
    • Abnormal muscle weakness
    • Psoriasis
Buy Gemfibrozil

Gemfibrozil

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Gemfibrozil is a lipid-lowering agent. It is used for:

  • Lowering high levels of fats in the blood such as triglycerides and cholesterol. It is used when diet and lifestyle changes such as an exercised have not reduced the lipids enough.
  • Prevention of cardiovascular events like a heart attack or angina pectoris among patients with high levels of cholesterol. It is also used among patients with a high risk of heart disease who cannot take statin medicines.

Gemfibrozil is a type of medicine known as fibrates. It helps lower the levels of bad cholesterol and triglycerides in people with pancreatic and cardiovascular disease. It works by:

  • Increasing the breakdown of triglycerides present in the body.
  • Decreasing the production of triglycerides in the liver.
  • Decreasing the production of LDL cholesterol “bad fats” by the liver. This causes the liver to take up excess LDL in the blood at the same time increasing the HDL “good fats” levels.
  • Reducing the risk of excess fats being deposited in the blood vessels of the heart also known as atherosclerosis.

Why Buy Gemfibrozil?

Gemfibrozil is an effective lipid-lowering agent. It can significantly lower the LDL and triglycerides in the blood as it raises the HDL. It is more effective than non-statin cholesterol-lowering drugs with fewer side effects. Gemfibrozil is available as generic and brand name versions.

How to Take Gemfibrozil?

Gemfibrozil comes in a tablet form that you need to take orally. Take it exactly as prescribed by your physician. The typical dose is 600 mg twice a day, 30 minutes before taking your meal. Take it at around the same time every day. Do not take more or less than what is prescribed. Do not stop taking Gemfibrozil without telling your doctor.

Things to Remember

  • It is important that you do regular exercise and eats a healthy diet while taking this medicine.
  • Avoid drinking excess alcohol because this may increase the risk of side effects on the muscle and liver problems. If you experience any muscle pain, spasm, tenderness or weakness contact your doctor right away.
  • Patients who are 70 years of age and above, with a decrease in kidney function and muscular disorder must use Gemfibrozil with care.
  • Do not use Gemfibrozil if you have:
    • Are pregnant or breastfeeding
    • Are allergic to any of its ingredients
    • With a decrease liver function
    • With a severely decreased kidney function
  • Gemfibrozil can interact with statins. It may interact with blood thinners, oral diabetes medication and insulin. Inform your doctor if you are taking any other medications.
Buy Atenolol

Medication Prescribed To Treat Hypertention and Prevent Angina Pectoris Symptoms.

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Atenolol is a prescription medication. It belongs to the group of drug known as beta-blockers. It is prescribed for the treatment and prevention of hypertension or high blood pressure. High blood pressure is a common but dreaded condition when left untreated. It can cause damages to the heart, blood vessels, brain, kidney and other parts of the body.

It is also prescribed to prevent angina pectoris (chest pain) symptoms. It improves the survival of patients after a heart attack. It may be also prescribed by doctors to treat irregular heartbeat, migraine headaches and alcohol withdrawal symptoms.

Atenolol is often taken along with other high blood pressure medications like diuretics or water pills. It works by blocking the action of natural chemicals known as epinephrine on the blood vessels and heart. Blocking the action of this chemical relaxes the blood vessels thus lowering the blood pressure and heart rate. This drug also helps decrease the workload of the heart.

How to use Atenolol?

Your dose depends on your condition, how severe is your condition and how you react to your first dose. Take Atenolol by mouth once or twice a day or as prescribed by your physician. Take this drug exactly as directed. Do not take this drug more than what is prescribed. Take it at around the same time every day. If you will not take it around the same time each day, your blood pressure may fluctuate too often. For a missed dose, take it as soon as you remember.

What are the side effects of Atenolol?

Some of the side effects are:

  • Constipation
  • cold hands and feet
  • diarrhea
  • headache
  • dizziness
  • reduced sex drive or impotence
  • unexplained tiredness
  • leg pain
  • shortness of breath
  • blood pressure that’s lower than usual

Serious side effects are:

  • Depression with signs like anxiety, tiredness and trouble focusing
  • Allergic reaction with symptoms like rash, fever, trouble breathing and swelling of hands, feet, legs and throat

Important Information

  • Do not take this drug if you are allergic to other beta blockers.
  • Atenolol may interact with other medications. Inform your doctor if you are taking any other drugs, vitamins and herbal supplements.
  • Alpha blockers may decrease blood pressure too much when taken with Atenolol.
  • Abrupt withdrawal may result in Ischemic heart disease and hypersensitivity.
  • Gradually reduce your dosage over 1-2 weeks if you plan to discontinue using this medication.
  • Do not take Atenolol if you have very low blood pressure.
Buy Amlodipine

Medication To Treat Coronary Artery Disease and Angina Pectoris

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Amlodipine is a long-acting calcium channel blockers. It is indicated for the treatment of hypertension or high blood pressure. It is also prescribed by doctors to treat conditions like:

  • Coronary artery disease (CAD) in patients without heart failure
  • Angina pectoris (chest pain) due to Coronary artery disease
  • Chronic stable angina due to activity and stress
  • Prinzmetal’s angina that occurs at rest

Lowering the blood pressure helps reduces the risk of patients from cardiovascular-related events such as heart attack and stroke. It also lowers the patient’s risk from having kidney problems, loss of vision and other problems.

Amlodipine belongs to the class of drug known as calcium channel blocker. This drug works by blocking the calcium from entering into the muscle along the walls of the blood vessels and into the heart muscle. Blocking the calcium widens the blood vessels thus improving the flow of blood and reducing the blood pressure. It relaxes the blood vessel so the heart won’t have to pump blood that hard.

How to use Amlodipine?

Amlodipine comes in a tablet of 2.5mg, 5mg and 10mg. Take this medication once a day. You can take it with or without food. The typical dose for an adult is 5mg a day with a maximum dose of 10mg a day. For adults who are fragile, small or have liver problems, they may start with 2.5mg a day. For children who are 6 to 17 years of age, their dose is 2.5 mg to 5 mg once a day. This medication may only control chest pain and blood pressure but it will not cure the underlying condition. Take this medication even if you feel well.

What are the side effects of amlodipine?

Some of the side effects of amlodipine are:

  • Headache
  • Flushing
  • Drowsiness
  • Stomach pain
  • Upset stomach
  • Excessive tiredness
  • Swelling of feet, hands, ankle and lower leg

Serious side effects are:

  • Fainting
  • Rapid heartbeat
  • Severe chest pain

If you will experience side effects not mentioned above, seek medication attention right away.

Important Information

  • Take amlodipine exactly as directed. Do not skip a dose nor double up a dose for a missed one.
  • Do not take the medicine if you are allergic to its active ingredient and if you have very low blood pressure.
  • People with severe obstructive coronary artery disease may experience worsening of chest pain and heart attack at the initial phase of the treatment.

Amlodipine can cause low blood pressure in people with heart valve problems known as aortic stenosis.