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Type 2 Diabetes Treatment

Type 2 Diabetes Treatment

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Type 2 Diabetes is a common type of diabetes. It is a disease that occurs when your blood glucose is too high. Blood glucose or blood sugar is the main source of energy and comes mainly from the food you eat. 

A hormone made by the pancreas called insulin helps glucose get into your cells to be used for energy. Your body doesn’t produce enough insulin or doesn’t use it efficiently if you have type 2 diabetes. In this case, too much glucose remains in your blood and not enough reaches your cells.

woman having a glass of water

Symptoms of Type 2 Diabetes

Symptoms of Type 2 Diabetes often develop slowly. You can be living with this disease for years and not know it. When symptoms are present, they may include:

  • Unintended weight loss
  • Fatigue
  • Blurred vision
  • Increased thirst
  • Frequent urination
  • Increased hunger
  • Numbness or tingling in the hands or feet
  • Areas of darkened skin, usually in the armpits and neck
  • Slow-healing sores
  • Frequent infections

Who Is At Risk Of Developing Type 2 Diabetes?

You are more likely to develop Type 2 Diabetes if you:

Complications of High Blood Sugar Levels 

Potential complications of high blood sugar levels from Type 2 diabetes can include:

  • Heart disease
  • Kidney disease
  • Skin conditions
  • Stroke
  • Urinary tract infections and bladder infections
  • Digestive problems
  • Eye problems
  • Hearing loss
  • Liver problems, including nonalcoholic fatty liver disease
  • Foot problems, including leg and foot ulcers
  • Gum disease and other mouth problems
  • Peripheral neuropathy (nerve damage)
  • Sexual dysfunction

Treatment for Type 2 Diabetes

check for blood sugar

These steps will help keep your blood sugar level closer to normal, which can delay or prevent complications.

1. Healthy Eating

  • Modest servings of low-fat dairy, low-fat meats, and fish
  • Healthy cooking oils, such as olive oil or canola oil
  • Fewer calories
  • A regular schedule for meals and healthy snacks
  • Fewer refined grains, starchy vegetables, and sweets
  • Smaller portion sizes
  • More high-fiber foods, such as fruits, nonstarchy vegetables, and whole grains

2. Physical Activity

Exercise is important for losing weight or maintaining a healthy weight. It also helps with regulating blood sugar levels. 

  • Aerobic exercise
  • Resistance exercise
  • Limit inactivity

3. Weight Loss

Blood sugar levels, cholesterol levels, triglycerides, and blood pressure are better controlled with weight loss. Overweight people may notice improvements in these factors after losing as little as 5% of their body weight. As you lose weight, you will see a greater impact on your health and disease management.

4. Monitoring Your Blood Sugar

Your doctor will direct you on how often to check your blood sugar level to make sure you remain within your target range. You should keep a record of your measurements to share with your doctor.

5. Diabetes Medications 

Diabetes medications that help lower insulin levels or insulin therapy may be prescribed by your doctor if diet and exercise are not sufficient to maintain your target blood sugar level. Diabetes medications that help lower insulin levels include the following.

Buy Atorvastatin

Medication To Reduce the Risk of Heart-Attack

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Atorvastatin is a prescription medication. It is used among patients with high level of cholesterol including patients with certain inherited cholesterol disorders. It is also used to reduce the risk of heart attack among patients with high blood pressure and who have at least three additional risk factors for heart disease like:

  • Having a type 2 diabetes
  • Family history of heart disease
  • Abnormalities on the ECG
  • An enlarged heart ventricles
  • Smoking
  • Being older than 55 years old

Atorvastatin belongs to the group of drug known as a statin or HMG CoA reductase inhibitors or lipid metabolism regulators. It helps lower the bad cholesterol such as the triglycerides and LDL or low-density lipoprotein while it raises the good cholesterol in the blood. Cholesterols are fats in your body which can be dangerous to your health if they are too much.

Statins work by reducing the amount of bad cholesterol in the blood. It prevents the cholesterol from building up in the arteries and from clogging the arteries. Lowering the bad fats raises the good fats thus decreasing the risk of heart attack. Lowering the bad cholesterols also helps prevent stroke among patients with diabetes.

How to use Atorvastatin?

The recommended dose for an adult is 10mg to 20mg once a day. Take this medication at night with or without food. The maximum dose for an adult should not exceed 80 mg a day. For children 10 to 17 years of age, their dose is 10 mg to 20 mg once a day.

If you are taking other medications, take it one hour before or 4 hours after taking Atorvastatin. Avoid drinking grapefruit juice while using this drug. Take this drug regularly to get the most benefit from it. Continue taking this drug even if you feel well.

What are the side effects of Atorvastatin?

Some of the side effects are:

  • Diarrhea
  • Joint pain
  • Confusion
  • Heartburn
  • A runny nose, coughing and sneezing
  • Trouble sleeping
  • Memory loss
  • Symptoms of high blood sugar

Serious side effects are:

  • Allergic reaction
  • Muscle damage with symptoms like unexplained muscle pain, discolored urine and weakness

Important Information

  • This medication is not suitable for pregnant women. It is not also advisable for patients with chronic liver disease to take this drug.
  • Statins like atorvastatin can cause serious muscle problems. Consult your doctor first before using this medication.
  • It is important to take this medication along with lifestyle change like having a proper diet, exercise, weight loss and by stopping smoking.

Medication To Treat Type 2 Diabetes

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Acarbose comes in a tablet medication form that you need to take by mouth. Your dose is based on the severity of your condition, your body weight and your other medical conditions. The recommended starting dose is 50 mg once a day. The maximum daily dose is 100mg three times a day. Take this medication at the first bite of your meal. Acarbose only works when there’s food in your stomach.

Take Acarbose regularly to keep your blood sugar level under control. Take it exactly as directed by your physician. Do not take more than what is recommended.

What are the side effects of Acarbose?

Some of the common side effects are:

  • Diarrhea
  • Flatulence
  • Stomach pain
  • Constipation
  • Rectal bleeding
  • Mucus discharge

Some of the serious side effects are:

  • Allergic reaction with symptoms like redness, rash and swelling of the skin
  • Liver problems with symptoms like stomach swelling, jaundice and pain in the upper right portion of the stomach
  • Shortness of breath
  • Decreased consciousness

Seek medical attention right away if you will experience symptoms of hyperglycemia such as:

  • Weakness
  • Blurred vision
  • Frequent urination
  • Extreme hunger

Important Information

  • Alcoholic beverages may cause a decrease in the blood sugar level while under this medication.
  • Do not take Acarbose if you are allergic to its active ingredient and if you have larger hernias, chronic intestinal conditions, colonic ulceration and partial intestinal blockage.
  • Several drugs may interact with Acarbose. Tell your doctor if you are taking any other medications.
  • Do not stop taking this drug. You will be unable to control your blood sugar level if you will stop taking this medication which can lead to complications like nerve damage, stroke and several other complications.
Buy Glipizide

Medication Useful in Treating Type 2 Diabetes

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Diabetes is a disease that occurs when your blood sugar (glucose) level is too high. Glucose is very important as it provides energy to the body. Insulin helps glucose to reach and provide energy to every cell of the body. If body becomes unable to make enough insulin, then the blood glucose remains in the blood and doesn’t provide energy to the cells of the body. This condition is called as Diabetes.

Glipizide SR is an oral anti-hyperglycemic medicine. It is useful as an alternative to insulin in patients who are having stable diabetes.

How does Glipizide SR works?

Glipizide SR belongs to the class of drugs known as sulfonylurea. It helps to treat type-2 diabetes. Insulin is an important natural substance. In Diabetes type-2 patient, your body’s cells are unable to respond to insulin as well as they should. Glipizide SR works by stimulating insulin secretion. It leads to more insulin secretion by beta cells of pancreatic islet tissue. It is used together with diet and exercise. The drug also helps the body to use insulin efficiently. This insulin helps lower the blood sugar level.

How to take Glipizide SR?

It is available in the form of tablets of 10 mg. Take it 30 minutes before your main meal of the day.

  • Adult usual dose- 5 mg every day 30 min before breakfast.
  • Maintenance dose- 5-10 mg 1 day first meal of the day.
  • Maximum dose- 20 mg 1 day.
  • Children– (0-17 years only) safety and efficacy is not established in case of children.
  • Senior dosage– (age 65 & above) lower dose of 2.5 mg 1 day is recommended.
  • Comments:-

-At least several days should pass for increase or change in the dosage level.

-In case of unsatisfactory result of single dose, dividend doses may be effective.

-The dose depends on medical condition & response to the treatment.

What are the uses of Glipizide SR?

  1. It is Generic drug used to treat type 2 diabetes.
  2. Best results are observed only with proper diet and exercise.
  3. Controlling high blood sugar level help prevent further damage to other parts of the body like.
  • Kidneys
  • Eyes
  • Nerves
  • Limbs
  • Function of sex organ.
  1. Lowers risk of heart attack or stroke.
  2. It causes the release of your body’s natural insulin.
  3. Helps your body to use insulin efficiently.

What are the Precautions in taking Glipizide SR?

  • It is important to consider certain conditions while you want to start with Glipizide SR. Inform your Doctor if you have/are,
  • Allergic to Glipizide SR or other ingredients in it.
  • Dental or any other surgery.
  • Any other allergies.
  • Pregnancy
  • Breast feeding.
  • Medical history of liver disease.
  • Kidney disease.
  • Thyroid disease.
  • Certain hormonal conditions.
  • Electrolyte imbalance.
  • Avoid alcohol. It may increase risks of developing low blood sugar level.
  • Call your Doctor immediately in case of any side effects like nausea, vomiting or stomach pain.
  • It may make you more sensitive to sun. Use sunscreen and other protective methods.

Cost of Glipizide SR (Generic and Brand).

Generic medicines are cheaper as compared to Brand ones. They do not include expenditure on pricing, packaging and advertising. They are cheap drug and same effective as the Brand ones.

  • Cost of generic Glipizide SR.

0Cost of 60 tablets of 10 mg costs $ 30, per unit costs is $ 0.5.

  • Cost of Brand Glucotrol.

Cost of 60 tablets of 10 mg costs $ 207.76, per unit costs $ 3.46.

Buy Pioglitazone & Metformin

Medication That Treats Type 2 Diabetes Who Don’t Take Insulin Injections

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Metformin and Pioglitazone is a combination of two medicines. It helps to control blood sugar levels. It is beneficial for people with type 2 diabetes who don’t use insulin injection every day.

Type 2 diabetes mellitus – It is a metabolic disease that is shows high blood sugar level, insulin resistance and relative lack of insulin.

Symptoms include,

  • Increased thirst.
  • Frequent Urination.
  • Weight loss.
  • Increased hunger.
  • Feeling tired.
  • Sores that do not heal.

The drug includes Metformin and Pioglitazone. The two agents control or improve sugar level in these patients. It is used in combination with diet and exercise.

How does Metformin- Pioglitazone works?

The drug includes two medicines-

Metformin – It belongs to the biguanides class of medication.

  • It improves glucose tolerance.
  • Lowers both basal and postprandial plasma glucose.
  • Decrease absorption of glucose in the intestine.
  • Decrease glucose production in the liver.
  • Improves insulin sensitivity by increasing peripheral glucose uptake and its utilization.

Pioglitazone: It belongs to the class of medication called as thiazolidinedione.

  • It decreases insulin resistance in the periphery and in the liver.
  • Increases insulin-dependent glucose disposal.
  • Decreases the glucose output from the liver.

They together help to control sugar level in patient with Diabetes mellitus type-2

How to take Metformin- Pioglitazone?

The drug comes in the form of a Tablet of strength 15/500 mg.

General Dose: one or two times in a day as prescribed by your Doctor.

Children: Safety and efficacy not established.

Geriatric: Dose is same as adult. Take care in case of patient >80 years for Renal function.

Maximum dose: 45 mg of pioglitazone/2550 mg of metformin.

Take it orally around the same time every day with food. The Dosage depend on

  • Your medical condition.
  • Your response to the treatment.
  • Other medications you take.

Your Doctor may ask you to start at a low dose and gradually increase it as needed.  Keep the track of the results and show your doctor. Your dosage /treatment may need to be changed if required by your Doctor.

What are the Uses of Metformin and Pioglitazone?

  1. The drug treats type 2 Diabetes who don’t take insulin injections.
  2. Helps to control sugar level with numerous mechanism as discussed above.
  3. Studies indicate that the drug improves sensitivity to insulin in muscle and adipose tissue.
  4. Improve sugar level control and reduce circulating insulin levels.
  5. Controlling high blood sugar helps prevent
  • Kidney damage.
  • Blindness.
  • Loss of limbs.
  • Sexual function problems.
  • Less risk of heart attack or stroke.
  1. Your Doctor may use it for other purposes not mentioned in the medication guide.

What are the Precautions in taking Metformin and Pioglitazone?

  • It is necessary to take precautions in certain cases. Inform your doctor if you have/are
  • Allergic to pioglitazone or Metformin.
  • Any other allergies.
  • Severe breathing problems or other lung diseases.
  • Blood problems like Anemia, Vitamin B 12 deficiency.
  • Kidney disease.
  • Liver disease.
  • Heart disease.
  • Fluid in your lungs.
  • Certain eye problems.
  • Bladder cancer.
  • This medication can cause changes in the Menstrual Cycle in Women.
  • Limit use of alcohol while using this medication.
  • Inform your doctor regarding surgery or x-ray/ scanning procedure using iodinated contrast.

Cost of Metformin/pioglitazone (Generic and Brand).

The cost of brand medicine increases due to the Brand name of the company. Its price also increases due to the packaging and pricing. They spend a lot of amount on the research and development of the drugs.

But the Generic drugs are cheaper than the brand ones. We order in bulk. Other several cost-cutting measures also reduce the cost of this drug. This is passed on to our customers.

Cost of Generic Metformin/pioglitazone.

Pack of 90 tablets of 15/500 mg costs $ 53.99, per unit cost is $ 0.6.

Cost of Brand Actoplus Met.

Pack of 90 tablets of 15/500 mg costs $ 992.38, per unit cost is $ 11.03.

Buy Glibenclamide & Metformin

Medication that Treats High Blood Sugar Levels in Type 2 Diabetes

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Type 2 diabetes is the most common form of diabetes. It is said as diabetes mellitus in medical term. Type 2 diabetes is described as a group of metabolic diseases in which the person has high blood glucose (sugar) there may be different reasons behind it. Like inadequate insulin production, improper response to insulin by your body cells or both.

Glyburide-metformin is a combination of two oral diabetes medicines. It helps in case of type 2 diabetes.

How do Glyburide-metformin works?

It belongs to the sulfonylurea class of insulin secretagogues. Certain cells in the pancreas are responsible to produce insulin known as beta cells.

Glyburide stimulates the function of this pancreatic beta cells. This allows it to produce insulin and reduce blood glucose.

Metformin is in the class of biguanides. It helps to improve glucose tolerance. It lowers basal and postprandial plasma glucose level. Metformin performs in three ways.

  1. Decreases glucose production in the liver.
  2. Decreases glucose absorption in the intestine.
  3. Increases peripheral glucose uptake and utilization.

All this helps to maintain low glucose level in your blood. In addition to the glucose level in your blood. In addition to glucose lowering actions, glyburide produces a mild diuresis by allowing renal free water clearance.

What are the uses of Glyburide-metformin?

Treats high blood sugar levels in type 2 diabetes. It is performed in combination with diet and exercise. Other uses are;

  • Helps your body to use insulin better.
  • Glyburide lowers the blood sugar level in the body.
  • It causes the pancreas to produce insulin.
  • Metformin helps to control the amount of glucose in your blood.
  • It decreases the amount of sugar you absorb from your body.
  • Decreases amount of glucose made by your liver.
  • It also helps your body to use its own insulin more effectively

How to take Glyburide-metformin?

Glyburide-metformin is available in the form of tablets of strength 5/500mg. Your dose form and how often you take may depend on,

  • Your age.
  • The condition being treated.
  • How serve your condition is?
  • Other medical condition you have.
  • Your reaction to the first dose.

Adult dosage: – [age 18-64 years]

  • Initial dose -12.5/250mg. Take it once or twice in a day with meals.
  • Maintenance dose – Doctor may increase the dose in increments of 1.25/250mg at two-week intervals.
  • The maximum dose – 20/200mg in a day.
  • For patients inadequately controlled on a sulfonylurea and/or metformin- 2.5/500 mg or 5/500 mg two times in a day with meals.
  • Children- Safety and efficacy in patients younger than 18 years have not been established.

What are the precautions in taking Glyburide-metformin?

It is important to take into consideration certain conditions in taking Glyburide-metformin. Inform or ask your doctor if you have/are,

  • Allergic to Glyburide-metformin.
  • Any other allergies.
  • Kidney disease.
  • Liver disease.
  • Congestive heart failure, recent heart attack etc.
  • Serious infection.
  • Dehydration.
  • Lung disease
  • Blood problems.
  • Fertility problems.
  • Dental or other surgery.
  • Tell your doctor about all medications you take.
  • Limit alcohol.

Other precautions are,

  • Sensitivity towards sun increases. Use sunscreen and wear protective clothing when outdoors.
  • Discuss a plan with your doctor to manage your blood sugar while pregnant.
  • Metformin passes into breast milk. Ask your doctor to use while breastfeeding.

Cost of Glyburide-metformin (Generic and brand).

Generic medicines are cheap but show the same effect. Both generic and brand version contain the same active ingredient. Brand drugs as costlier as compared to generic drugs. The increased cost is due to the pricing, packaging and the brand name of the company.

Cost of generic Glyburide-metformin.

Pack of 30tablets of strength 5mg/500mg costs $ 8 per unit cost is $ 0.27.

Cost of brand Glucovance.

Pack of 30 tablets of strength 5mg/500mg cost $ 49.63 per unit cost is $ 1.65.