Cyclosporine is a cyclic polypeptide of 11 amino acids. It is produced by a fungal species which has immune-suppressive properties. It shows specific action on T cells and the cellular immune response.
Dry eye is a condition in which a person doesn’t have enough tears that lubricate and nourish the eye. It is a condition caused by inflammation of eyes. Tears play an important role to maintain the health of the front surface of the eyes. It also helps to provide clear vision and reduce the risk of infection etc. Many vital functions are done by the tears. Dry eyes occur when the balance between the production and drainage of tear is disturbed.
Cyclosporine is an ophthalmic solution used to increase tear production in people with dry eye disease. It was approved by FDA in January 2003.
How does dose Cyclosporine work?
Cyclosporine belongs to the class of medications known as immune-suppressants. It helps to increase tear production in people with dry eye disease. It decreases swelling in the eye to allow the production of tears.
The solutions is thought to work locally in the eyes as a partial modulator of the immune system. A lymphocyte is a type of white blood cell of the immune system. A condition may occur where these cells may die and accumulate in the tear glands. Cyclosporine can reserve this condition and lead to increase in tear production. The treatment may take 3 to 6 months to shows increase in tears production.
What are the uses of cyclosporine?
How to use the ophthalmic Cyclosporine?
Cyclosporine is available in the form of an ophthalmic solution of 3 ml bottles (strength 0.05%).
What are the precautions in using Cyclosporine?
Cost of cyclosporine (generic & brand).
Generic medicines does not need to spend much on research and development of the drug. Other costs like the commission to agents etc. are also saved due to direct sourcing from the manufacturer. Another cost-cutting method allows us to sell cheap generic medicine to our customers.
Brand drugs include cost spend on advertising packaging and pricing. It also spends a lot of amounts on advertising their brand name. So the brand medicine is always costlier.
Cost of Generic Cyclosporine.
1 Bottle of 3 ml of 0.05 % of Cyclosporine cost $ 24.
Cost of Brand sandimmune.
1 ampule of 5 ml (50 mg/ml) costs $ 64.80.