Tizanidine reduces skeletal muscle tone by a selective action in cerebrospinal axis, without altering consciousness. Tizanidine selectively depresses spinal and supraspinal polysynaptic reflexes involved in regulation of muscle tone. Zanaflex depresses polysynaptic pathways in ascending reticular formation, which are involved in wakefulness. Zanaflex has no effect on neuromuscular transmission and on muscle fibers. Tizanidine reduces rigidity, upper motor neurone spasticity and hyperreflexia
How Does Tizanidine Works?
Tizanidine inhibits release of excitatory amino acids in spinal interneurones. Zanaflex facilitates inhibitor transmitter glycine. Tizanidine inhibits polysynaptic reflexes, reduces muscle tone and frequency of muscle spasms.
Side effects of Tizanidine / Generic of Zanaflex, Sirdalud
The common side effects reported with Zanaflex are dry Mouth, somnolence, asthenia, dizziness, UTI, constipation, liver function tests abnormal, vomiting, speech disorder, blurred vision, urinary frequency, flu symptom, dyskinesia, nervousness, pharyngitis and rhinitis.
Guidelines before using Tizanidine / Generic of Zanaflex, Sirdalud
Tizanidine should be used with caution in patients with renal insufficiency. The concomitant use of Tizanidine and oral contraceptives should be avoided. The dose of Zanaflex should be reduced in elderly patients. Tizanidine is not administered to pediatric patients. Zanaflex should not be given to pregnant women. If it is an absolute must to take Zanaflex during pregnancy, it should be administered under the supervision of a medical practitioner. Zanaflex is not given to nursing mothers as it can pass in to breast milk. Tizanidine should not be used for long duration in high dose as it can cause orthostatic hypotension. . The patient should be advised to avoid activities that require alertness and concentration like operating machinery and driving as Tizanidine causes sedation. Avoid alcohol while on Tizanidine treatment.
What are the common dosages of Tizanidine / Generic of Zanaflex, Sirdalud?
The recommended dosage of 8 mg of tizanidine reduces muscle tone in patients with spasticity for a period of several hours.
Difference between Brand and Generic Tizanidine
The active ingredient is Tizanidine in both brand and generic forms because of which the mechanism of action and drug interactions are the same. The difference between brand and generic forms are packaging, pricing and the brand name. Generic variants are priced cheaper because there are no brand names associated with it as well as no expenses towards research and development. You can purchase cheap Zanaflex medicine when it is sold as a generic variant.
Where and How to buy Tizanidine / Generic of Zanaflex, Sirdalud?
You can easily buy Tizanidine online at Rx 2 Go Pharmacy. When you order Zanaflex drug online from us, it will reach your doorstep without any hassles. You can also save more when you buy Zanaflex online in more numbers with the volume discounts we offer.
Why is the price of Tizanidine / Generic of Zanaflex, Sirdalud so cheap at Rx 2 Go Pharmacy?
There are various cost reduction measures that we undertake to provide the best quality generic drugs at the cheapest prices to our customers. We directly source the drugs in bulk quantities from the manufacturers, which help us negotiate better prices. These cost saving measures translate to cheaper prices of prescription drugs at R2 Go Pharmacy.
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