Clindamycin inhibits most gram-positive cocci and a variety of anaerobes. The oral absorption of Cleocin is good and it penetrates to most skeletal tissues and soft tissues. Cleocin does not cross brain and CSF. Clindamycin accumulates in neutrophils and macrophages. Clindamycin is indicated for the treatment of anaerobic and mixed infections causing abdominal, pelvic and lung abscesses. In AIDS patient Cleocin is combined with pyrimethamine for toxoplasmosis and with primaquine for pneumocystis carnii pneumonia. You can buy Clindamycin here at Rx 2 Go Pharmacy and enjoy the heavy volume discounts we offer.
Cleocin acts by inhibiting bacterial protein synthesis. Cleocin combines with 50S ribosome subunits and interferes with the translocation process. Cleocin acts by interfering with the bacteria’s cell wall formation. This weakens the cell wall, causing it to rupture, and kills the bacteria.
The common side effects reported with Clindamycin during clinical trials and during post marketing are abdominal pain, pseudomembranous colitis, esophagitis, nausea, vomiting, diarrhea, mild to moderate morbilliform-like maculopapular skin rashes, pruritus, vaginitis, exfoliative dermatitis,jaundice, abnormalities in liver function tests, azotemia, oliguria, proteinuria, transient neutropenia and eosinophilia polyarthritis.
Clindamycin should be taken with a full glass of water to avoid esophageal irritation. Cleocin should not be given along with neuromuscular blocking agents. Cleocin and Erythromycin exhibit partial cross-resistance invitro. Hence Clindamycin and Erythromycin should not be administered together. The use of Clindamycin is contraindicated in patients with a history of gastrointestinal disease, particularly colitis. Cleocin should be used with caution in atopic individuals. There is no need of dosage adjustments in patients with renal disease. The dose of Cleocin should be reduced in patients with hepatic impairment. Clindamycin is used during pregnancy only if clearly needed. Clindamycin is not recommended for use by lactating mothers as it gets excreted in to breast milk.
The recommended starting dose of Clindamycin for severe infection is 150-450mg every 6 hours. The dose of Cleocin in pediatric patients is 8 to 20 mg/kg/day divided into three or four equal doses.
The active ingredient is Clindamycin in both brand and generic forms because of which the mechanism of action and drug interactions are the same. The difference between brand and generic forms are packaging, pricing and the brand name. Generic variants are priced cheaper because there are no brand names associated with it as well as no expenses towards research and development. You can buy cheap Cleocin medicine when it is sold as a generic variant.
You can purchase Cleocin medicine online from our pharmacy. When you order Cleocin drug online from us, it will reach your doorstep without any hassles. You can also save more when you buy Cleocin online in more numbers with the volume discounts we offer.
At Rx 2 Go Pharmacy we are continuously improvising on means to reduce costs. Our expenses towards research and development are zero. We source the prescription drugs directly from the manufacturers and the price benefits on bulk ordering are passed on to our customers.
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