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Alendronate Sodium

Alendronate Sodium is a medication indicated for the treatment and prevention of osteoporosis in post-menopausal women. Osteoporosis is a condition in which the bones become thin and weak and easily breaks

It’s also used to treat osteoporosis in men and women who are having a long-term treatment with corticosteroid, a type of medication that may cause osteoporosis in some patients such as Prednisolone. Alendronate can also treat Paget’s disease of bone, a condition in which the bones become soft, weak and may be painful, deformed or easily broken.

Alendronate is a type of bisphosphonate medication that prevents the breakdown of the bone. It works by preventing the breakdown of the bone and by increasing its thickness to make it strong and keep it from breaking including those of the spine and hip. Alendronate binds very tightly to the bone thus preventing the calcium from being removed by the osteoclasts. This stops the osteoclasts from breaking the bones, making it strong and less likely to break.

Why Buy Alendronate Sodium?

Alendronate is mostly prescribed medications for the treatment and prevention of osteoporosis. It was approved for medical use in the US since 1995. It’s one of the most prescribed medications in the US with more than 10 million prescriptions. Alendronate is available as generic and brand names in the market. The generic version is cheaper than the brand names but both versions contain the same active ingredient and the same mechanism of action.

How to Take Alendronate Sodium?

Alendronate sodium comes in tablet form for you to take by mouth. It comes in 5mg and 10 mg tablet that you can take once a week or a 35 mg and 70 mg tablet taken once a week. The 40 mg tablet is usually taken once a day for 6 months to treat Paget’s disease of bone.

Alendronate may cause ulcer of the esophagus or may not work properly if not taken accordingly. Take this medicine in the morning on an empty stomach or just after you get out of the bed in the morning. Do not take it before bedtime. Swallow the tablet whole with plenty of water, at least 2 cups. Never take it with coffee, juice, tea or other liquid other than plain water. Do not chew or crush the tablet. After taking it, do not drink, eat or take other medications. Wait for at least 30 minutes. Do not also lie down for at least 30 minutes after taking Alendronate.

Alendronate sodium can only control Paget’s disease and osteoporosis but it will not cure them. Continue taking it even if you feel well for it may take 3 months or longer for your bone density starts to increase. It will only treat and prevent osteoporosis as long as you are taking it regularly.

What are the side effects of Alendronate Sodium?

Alendronate may cause unwanted side effects aside from its intended effects. Common side effects include:

  • Diarrhea
  • Nausea
  • Vomiting
  • Joint and muscle pain
  • Acid reflux
  • Constipation
  • Stomach upset
  • Stomach pain

These effects are mild and may go away within a few days. If they become more severe or won’t go away, call your doctor.

Serious side effects include:

  • Erosion or ulcers on your esophagus with signs like:
    • Pain when swallowing
    • Bloody vomit
    • Trouble swallowing
    • Heartburn
    • Chest pain
  • Bone death on your jaw with signs like:
    • Numbness feeling in your jaw
    • Swollen, painful gums
    • Loosening of your teeth
    • Poor healing of your jaw
  • Severe joint, bone and muscle pain
  • Unusual break in the hipbone and leg bones with signs like:
    • Dull, aching pain in your hips, thigh or groin
  • Low blood calcium level with signs like:
    • Muscle spasm
    • Muscle cramps
    • Numbness in your finger, toes and around your mouth

In case of serious side effects contact your physician immediately.

We care for your safety

  • The duration of your treatment differs from other patients. Your doctor will re-assess your risk of bone fracture after 3-5 years of treatment. Your doctor will determine whether you will continue with the treatment or stop based on your assessment.
  • If you are using this to treat osteoporosis due to long-term use of corticosteroid, keep taking it as long as you keep taking corticosteroid.
  • Alendronate may interact with other medications. Before using this, tell your doctor of your other medications including prescription and non-prescription drugs, vitamins and herbal supplements. Taking it with certain medications may cause more side effects such as ulcers in your esophagus and other gastrointestinal problems. Sometimes, it can make your drug less effective when combined with supplements like iron, calcium, magnesium and antacids. See to it that you wait at least 30 minutes before or after taking this medicine.
  • This medicine can cause severe bone and muscle pain. In case you have these symptoms stop taking this medicine and contact your doctor as soon as possible. This drug can also cause osteonecrosis of the jaw, a condition where there is insufficient supply of blood to the jaw causing bone death.

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